Evaluation of the potential of 188Re-PEI-MP for therapy of bladder carcinoma and 99mTc-PEI-MP for diagnosis and follow up

Ferreira, Sara; Laranjo, Mafalda; Abrantes, Ana Margarida; Brito, Ana; Metello, Luís F.; Zeevart, Jan; Louw, Werner; Dormehl, Irene; Botelho, Maria Filomena

http://hdl.handle.net/10400.22/6455

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
XXI Porto Cancer Meeting_2012.pdf		242.9 KB	Adobe PDF	Download

Send Feedback

Authors

Ferreira, Sara

Laranjo, Mafalda

Abrantes, Ana Margarida

Botelho, Maria Filomena

Abstract(s)

The development of water-soluble polymers such as PEI-MP (polyethyleneimine, functionalised with methylphosphonate groups) that might be labeled with 188Re (emits of high energy beta particles) and 99mTc are recent approaches, with a strong potential for metabolic radiotherapy and diagnosis, respectively. The aim of this study was to evaluate the efficacy of 188Re-PEI-MP as therapeutic agent for bladder carcinoma and 99mTc-PEI-MP for its diagnosis and follow up.