Morphofunctional characterization of the ileum in a type 1 diabetes rat model 7

Henriques, Vanessa Mendes; Monteiro, Salomé Gonçalves; Vieira, Filipa Quintela; Sá, Paulo  Correia de; Araújo, Margarida Duarte

http://hdl.handle.net/10400.22/20244

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Authors

Henriques, Vanessa Mendes

Monteiro, Salomé Gonçalves

Vieira, Filipa Quintela

Sá, Paulo Correia de

Araújo, Margarida Duarte

Abstract(s)

Diabetes mellitus (DM) is a metabolic disorder that affects 1 in 12 people with high mortality and morbidity. Knowing that about 76% of diabetic patients have gastrointestinal complications, we decided to characterize morphologically and functionally the ileum of a rat (Rattus norvegicus, Wistar) model that mimics type 1 DM. Diabetes was chemically induced by a single intraperitoneal injection of streptozotocin (STZ, 55mg/kg). All animals were used 14 days after injection with saline (CTRL-group) or STZ (STZ-group).

URI

http://hdl.handle.net/10400.22/20244

Citation

Mendes-Henriques, V., Gonçalves-Monteiro, S., Vieira, F. Q., Correia-de Sá, P., & Duarte-Araújo, M. (2015). Morphofunctional characterization of the ileum in a type 1 diabetes rat model 7. In R. A. Silva, P. Baylina, F. Q. Vieira, C. Barrias, M. Rubim, T. Coelho, C. Prudêncio, & Â. Jesus (Eds.), II Congresso Internacional da Saúde Gaia Porto: Livro de Resumos (1st ed., Vol. 1, pp. 181). Escola Superior de Tecnologia da Saúde do Instituto Politécnico do Porto.