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Picocyanobacteria from a clade of marine cyanobium revealed bioactive potential against microalgae, bacteria, and marine

dc.contributor.authorCosta, Maria Sofia
dc.contributor.authorCosta, Margarida
dc.contributor.authorRamos, Vitor
dc.contributor.authorLeão, Pedro N.
dc.contributor.authorBarreiro, Aldo
dc.contributor.authorVasconcelos, Vítor
dc.contributor.authorMartins, Rosario
dc.date.accessioned2015-06-11T09:27:57Z
dc.date.available2015-06-11T09:27:57Z
dc.date.issued2015
dc.description.abstractThe production of bioactive compounds either toxic or with pharmacological applications by cyanobacteria is well established. However, picoplanktonic forms within this group of organisms have rarely been studied in this context. In this study, the toxicological potential of picocyanobacteria from a clade of marine Cyanobium strains isolated from the Portuguese coast was examined using different biological models. First, strains were identified by applying morphological and molecular approaches and cultured under lab conditions. A crude extract and three fractions reflecting a preliminary segregation of lipophilic metabolites were tested for toxicity with the marine microalga Nannochloropsis sp., the bacteria Pseudomonas sp., the brine shrimp Artemia salina, and fertilized eggs of the sea urchin Paracentrotus lividus. No significant apparent adverse effects were noted against Artemia salina. However, significant adverse effects were found in all other assays, with an inhibition of Nannochloropsis sp. and Pseudomonas sp. growth and marked reduction in Paracentrotus lividus larvae length. The results obtained indicated that Cyanobium genus may serve as a potential source of interesting bioactive compounds and emphasize the importance of also studying smaller picoplanktonic fractions of marine cyanobacteria.por
dc.identifier.citationCosta, M. S., Costa, M., Ramos, V., Leão, P. N., Barreiro, A., Vasconcelos, V., & Martins, R. (2015). Picocyanobacteria From a Clade of Marine Cyanobium Revealed Bioactive Potential Against Microalgae, Bacteria, and Marine Invertebrates. Journal of Toxicology and Environmental Health, Part A, 78(7), 432–442. https://doi.org/10.1080/15287394.2014.991466
dc.identifier.doi10.1080/15287394.2014.991466
dc.identifier.urihttp://hdl.handle.net/10400.22/6276
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherTaylor & Francispor
dc.relation.publisherversionhttp://www.tandfonline.com/doi/pdf/10.1080/15287394.2014.991466por
dc.titlePicocyanobacteria from a clade of marine cyanobium revealed bioactive potential against microalgae, bacteria, and marinepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage442por
oaire.citation.startPage432por
oaire.citation.titleJournal of Toxicology and Environmental Health, Part A: Current Issuespor
oaire.citation.volume78por
person.familyNameMartins
person.givenNameRosario
person.identifier.ciencia-idA919-DB40-EF10
person.identifier.orcid0000-0002-9882-4651
person.identifier.scopus-author-id21834368700
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication82a7c349-c88e-450f-adc7-3331d69149cf
relation.isAuthorOfPublication.latestForDiscovery82a7c349-c88e-450f-adc7-3331d69149cf

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