Repository logo
 
Publication

Cone beam CT (CBCT) in radiotherapy: Assessment of doses using a pragmatic setup in an international setting

dc.contributor.authorDjukelic, Mario
dc.contributor.authorSá, Ana Cravo
dc.date.accessioned2025-10-21T10:20:38Z
dc.date.available2025-10-21T10:20:38Z
dc.date.issued2025-03
dc.description.abstractThe imaging modality kV CBCT on linear accelerators (linacs) is utilised to verify positioning and anatomy in cancer patients undergoing radiotherapy treatment. There is a need for optimisation of radiological protection in kV CBCT imaging protocols to avoid unnecessarily high exposures to normal tissues surrounding the target. A network of ICRP mentees from 23 countries were surveyed for available dosimetry equipment. Standardised measurements on CBCT linac imaging systems were conducted using a cone beam dose index (CBDI) devised as a straightforward measurement for wide beam doses. Measurements were made with (a) 100 mm ionisation chambers or (b) 0.6 cc Farmer ionisation chambers and cylindrical CT PMMA phantoms, and (c) an alternative setup of Farmer chambers and cubical phantoms comprised of slabs of water equivalent material readily available in radiotherapy centres. The measurements were compared with Monte Carlo (MC) simulations. The survey showed limited availability for the reference setup using 100 mm chambers and CT phantoms. Correction factors were derived to convert normalised CBDI from alternative setups to the reference setup and are on average within 2% of MC simulations. The slab phantom in combination with a Farmer chamber provides an alternative to quantify CBCT radiation dose indices from linac-based image-guided radiotherapy using materials accessible in most centres worldwide. A method is presented to use correction factors for Varian Truebeam linacs if traditional 100 mm chambers and cylindrical CT phantoms are not available. This will enable most radiotherapy centres across the world to engage in meaningful imaging dose measurement and optimisation.por
dc.identifier.citationDjukelic, M., Martin, C. J., Abuhaimed, A., Kron, T., Gros, S., Wood, T., Pankowski, P., Ung, N. M., Vassileva, J., Plazas, M. C., Vostinic, S., Lazovic, A., Sá, A. C., Nilsson, I., Koutrouli, M., Murugan, L., Fourie, H., Miadzvetski, A., Ameri, B. A., … Small, W. (2025). Cone beam CT (CBCT) in radiotherapy: Assessment of doses using a pragmatic setup in an international setting. Physica Medica, 131, 104937. https://doi.org/10.1016/j.ejmp.2025.104937
dc.identifier.doi10.1016/j.ejmp.2025.104937
dc.identifier.eissn1724-191X
dc.identifier.issn1120-1797
dc.identifier.urihttp://hdl.handle.net/10400.22/30658
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.relation.hasversionhttps://www.sciencedirect.com/science/article/pii/S112017972500047X?via%3Dihub
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectImage-guided radiotherapy
dc.subjectkV cone beam computed tomography
dc.subjectCone beam dose index
dc.subjectWater equivalent phantom
dc.subjectOn-board imager
dc.subjectDosimetry
dc.subjectFarmer ionisation chamber
dc.subjectCorrection factor
dc.titleCone beam CT (CBCT) in radiotherapy: Assessment of doses using a pragmatic setup in an international settingpor
dc.typeresearch article
dspace.entity.typePublication
oaire.citation.titlePhysica Medica
oaire.citation.volume131
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ART_Ana Cravo Sá.pdf
Size:
1.91 MB
Format:
Adobe Portable Document Format
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
4.03 KB
Format:
Item-specific license agreed upon to submission
Description: