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An in vivo study to analyse the potential of 188Re-PEI-MP for metabolic radiotherapy of osteosarcoma and bladder carcinoma

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Introduction: 188Re is a promising radionuclide for metabolic therapy because of the emission of high energy beta-particles. The development of water-soluble polymers such as PEI-MP (polyethyleneimine, functionalised with methylphosphonate groups) that might be labeled with 188Re are recent approaches, with a strong potential for metabolic radiotherapy.

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