Publicação
An overview of the therapeutic potential of dimeric flavonoids for targeting cancer hallmarks
| dc.contributor.author | Lopes, Inês | |
| dc.contributor.author | Meireles, Isabel | |
| dc.contributor.author | Rocha, Rafaela | |
| dc.contributor.author | Medeiros, Rui | |
| dc.contributor.author | Cerqueira, Fátima | |
| dc.date.accessioned | 2025-10-21T10:21:11Z | |
| dc.date.available | 2025-10-21T10:21:11Z | |
| dc.date.issued | 2025-01-14 | |
| dc.description.abstract | Evidence found in the literature indicates that dimeric flavonoids constitute important therapeutic options against cancer. Using these molecules to prevent cancer progression might be a novel and promising therapeutic approach with advantages like fewer side effects, easy access in nature, overall health benefits and overcoming drug resistance. Cancer is a complex disease and still not understood, but there are some common mechanisms and biological characteristics underlying tumor progression that have been scrutinized over the years. This information was summarized in a conceptual framework designated as hallmarks of cancer. Dimeric flavonoids exert biological effects in several pathways involved in cancer hallmarks including cell growth, cell cycle, apoptosis, metastasis and metabolism. | por |
| dc.identifier.citation | Lopes, I., Meireles, I., Rocha, R., Medeiros, R., & Cerqueira, F. (2025). An Overview of the Therapeutic Potential of Dimeric Flavonoids for Targeting Cancer Hallmarks. BioChem, 5(1), 2. https://doi.org/10.3390/biochem5010002 | |
| dc.identifier.doi | 10.3390/biochem5010002 | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/30660 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | MDPI | |
| dc.relation | PI86-CI-IPOP-66-2019 | |
| dc.relation.hasversion | https://www.mdpi.com/2673-6411/5/1/2 | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Cancer | |
| dc.subject | Drug resistance | |
| dc.subject | Dimeric flavonoids | |
| dc.subject | Hallmarks | |
| dc.title | An overview of the therapeutic potential of dimeric flavonoids for targeting cancer hallmarks | por |
| dc.type | research article | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 1 | |
| oaire.citation.title | BioChem | |
| oaire.citation.volume | 5 | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 |