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An overview of the therapeutic potential of dimeric flavonoids for targeting cancer hallmarks
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Orientador(es)
Resumo(s)
Evidence found in the literature indicates that dimeric flavonoids constitute important therapeutic options against cancer. Using these molecules to prevent cancer progression might be a novel and promising therapeutic approach with advantages like fewer side effects, easy access in nature, overall health benefits and overcoming drug resistance. Cancer is a complex disease and still not understood, but there are some common mechanisms and biological characteristics underlying tumor progression that have been scrutinized over the years. This information was summarized in a conceptual framework designated as hallmarks of cancer. Dimeric flavonoids exert biological effects in several pathways involved in cancer hallmarks including cell growth, cell cycle, apoptosis, metastasis and metabolism.
Descrição
Palavras-chave
Cancer Drug resistance Dimeric flavonoids Hallmarks
Contexto Educativo
Citação
Lopes, I., Meireles, I., Rocha, R., Medeiros, R., & Cerqueira, F. (2025). An Overview of the Therapeutic Potential of Dimeric Flavonoids for Targeting Cancer Hallmarks. BioChem, 5(1), 2. https://doi.org/10.3390/biochem5010002
Editora
MDPI