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Cyanobacteria and microalgae bioactive compounds in skin-ageing: potential to restore extracellular matrix filling and overcome hyperpigmentation

dc.contributor.authorFavas, Rita
dc.contributor.authorMorone, Janaina
dc.contributor.authorMartins, Rosário
dc.contributor.authorVasconcelos, Vítor
dc.contributor.authorLopes, Graciliana
dc.date.accessioned2021-09-02T14:57:40Z
dc.date.available2021-09-02T14:57:40Z
dc.date.issued2021-08-06
dc.description.abstractAs the largest organ in human body, skin acts as a physicochemical barrier, offering protection against harmful environmental stressors, such as chemicals, pathogens, temperature and radiation. Nonetheless, skins prominence goes further, with a significant psychosocial role in an increasingly ageing population. Prompted by consumers’ concern regarding skincare, cosmetic industry has been developing new formulas capable of lessening the most visible signs of ageing, including reduction in skin density and elasticity, wrinkling and hyperpigmentation. Allied to skincare is the rising importance set on natural products, sustainably obtained from less environmental impacting methods. Cyanobacteria and microalgae are adding importance in this field, given their ability to biosynthesize secondary metabolites with anti-ageing potential. In this review, we present an overview on the potential of cyanobacteria and microalgae compounds to overcome skin-ageing, essentially by exploring their effects on the metalloproteinases collagenase, elastase, gelatinase and hyaluronidase, and in other enzymes involved in the pigmentation process.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRita Favas, Janaína Morone, Rosário Martins, Vitor Vasconcelos & Graciliana Lopes (2021) Cyanobacteria and microalgae bioactive compounds in skin-ageing: potential to restore extracellular matrix filling and overcome hyperpigmentation, Journal of Enzyme Inhibition and Medicinal Chemistry, 36:1, 1829-1838, DOI: 10.1080/14756366.2021.1960830pt_PT
dc.identifier.doi10.1080/14756366.2021.1960830pt_PT
dc.identifier.issn1475-6374
dc.identifier.urihttp://hdl.handle.net/10400.22/18300
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor and Francispt_PT
dc.relation.publisherversionhttps://www.tandfonline.com/doi/full/10.1080/14756366.2021.1960830pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectSkin ageingpt_PT
dc.subjectMatrix metalloproteinasespt_PT
dc.subjectCollagenasept_PT
dc.subjectElastasept_PT
dc.subjectHyaluronidasept_PT
dc.subjectHyperpigmentationpt_PT
dc.titleCyanobacteria and microalgae bioactive compounds in skin-ageing: potential to restore extracellular matrix filling and overcome hyperpigmentationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleJournal of Enzyme Inhibition and Medicinal Chemistrypt_PT
oaire.citation.volume36pt_PT
person.familyNameMartins
person.givenNameRosario
person.identifier.ciencia-idA919-DB40-EF10
person.identifier.orcid0000-0002-9882-4651
person.identifier.scopus-author-id21834368700
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication82a7c349-c88e-450f-adc7-3331d69149cf
relation.isAuthorOfPublication.latestForDiscovery82a7c349-c88e-450f-adc7-3331d69149cf

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