Publicação
Can collagen membrane on bone graft interfere with light transmission and influence tissue neoformation during photobiomodulation? A preliminary study
| dc.contributor.author | Varela, Paulo Jorge Romão | |
| dc.contributor.author | Barros, Piedade | |
| dc.contributor.author | Montagner, Pedro Giorgetti | |
| dc.contributor.author | Provout, Michelle B. | |
| dc.contributor.author | Martinez, Elizabeth F. | |
| dc.contributor.author | Suzuki, Selly Sayuri | |
| dc.contributor.author | Garcez, Aguinaldo Silva | |
| dc.contributor.author | Gonçalves de Barros, Piedade Aurora | |
| dc.date.accessioned | 2026-09-10T10:41:39Z | |
| dc.date.available | 2026-09-10T10:41:39Z | |
| dc.date.issued | 2023-04-17 | |
| dc.description.abstract | This study qualitatively and quantitatively evaluated the transmission of light through a collagen membrane and the consequent local bone formation in a critical bone defect in vitro and in an animal model. Currently, bone substitutes and collagen membranes are used to promote new bone formation; however, when associated with photobiomodulation, biomaterials can act as a barrier, hindering the passage of light radiation to the area to be treated. Light transmittance was evaluated in vitro with a power meter and a 100 mW, 808 nm laser source with and without membrane. Twenty-four male rats received a critical surgical defect of 5 mm in diameter in the calvarial bone, subsequently a biomaterial (Bio-Oss; Geistlich®, Switzerland) was applied, and the animals were divided into the following three groups: G1—collagen membrane and no irradiation; G2—collagen membrane and photobiomodulation (irradiation with 4 J of 808 nm); and G3—photobiomodulation (4 J) followed by a collagen membrane. Histomophometric analyses were performed at 7 and 14 days after euthanasia. The membrane reduced the light transmittance (808 nm) by an average of 78%. Histomophometric analyses showed significant differences in new blood vessels on day 7 and bone neoformation on day 14. Irradiation without membrane interposition resulted in a 15% more neoformed bone compared with the control (G1), and 6.5% more bone compared with irradiation over the membrane (G2). The collagen membrane interferes with light penetration during photobiomodulation, decreases light dosimetry on the wound area, and interferes with bone neoformation. | eng |
| dc.identifier.citation | Varela, P. J. R., Barros, P. A. G., Montagner, P. G., Provout, M. B., Martinez, E. F., Suzuki, S. S., & Garcez, A. S. (2023). Can Collagen Membrane on Bone Graft Interfere with Light Transmission and Influence Tissue Neoformation During Photobiomodulation? A Preliminary Study. Photobiomodulation, Photomedicine, and Laser Surgery, 2, 41(4), 167–174. https://doi.org/10.1089/photob.2022.0070 | |
| dc.identifier.doi | 10.1089/photob.2022.0070 | |
| dc.identifier.eissn | 2578-5478 | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/32695 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | SAGE Journals | |
| dc.relation.hasversion | https://journals.sagepub.com/doi/full/10.1089/photob.2022.0070 | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | |
| dc.subject | Low-level laser | |
| dc.subject | Laser therapy | |
| dc.subject | Bone graft | |
| dc.subject | Bone remodeling | |
| dc.title | Can collagen membrane on bone graft interfere with light transmission and influence tissue neoformation during photobiomodulation? A preliminary study | eng |
| dc.type | research article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 8 | |
| oaire.citation.issue | 4 | |
| oaire.citation.startPage | 1 | |
| oaire.citation.title | Photobiomodulation, Photomedicine, and Laser Surgery | |
| oaire.citation.volume | 41 | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
| person.familyName | Gonçalves de Barros | |
| person.givenName | Piedade Aurora | |
| person.identifier.ciencia-id | D210-6003-454B | |
| person.identifier.orcid | 0000-0002-2635-251X | |
| person.identifier.scopus-author-id | 23981959400 | |
| relation.isAuthorOfPublication | a85b368a-8f13-45eb-a744-7c5810a38e2c | |
| relation.isAuthorOfPublication.latestForDiscovery | a85b368a-8f13-45eb-a744-7c5810a38e2c |