A microfluidics technique to evaluate Staphylococcus aureus adhesion to micropatterned silica surfaces

Pinto, Liliana; Monteiro, Fernando Jorge; Carvalho, Ângela

http://hdl.handle.net/10400.22/25661

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Authors

Pinto, Liliana

Monteiro, Fernando Jorge

Carvalho, Ângela

Abstract(s)

Postoperative complications like poor osteointegration or bacterial adhesion to bone implants are the most common causes that lead to implant failure. Micropatterned surfaces have been used to improve implant osteointegration as they have shown to promote enhanced cellular attachment, proliferation and differentiation. It is well established that modifying the surface topography of a biomaterial has a positive effect on regeneration. However, a concern related to using implants with greater surface area and roughness is that bacterial adhesion might be increased. This study intends to evaluate the bacterial adhesion of S. aureus to micropatterned silica surfaces, proposed to be applied as bioactive coatings for bioinert hard-ceramic implants.

Keywords

Postoperative complications Bone implants

URI

http://hdl.handle.net/10400.22/25661

Citation

Pinto, L., Monteiro, F. J., & Carvalho, Â. (2018). A microfluidics technique to evaluate Staphylococcus aureus adhesion to micropatterned silica surfaces. Book of abstracts of the III Encontro de Biotecnologia Medicinal/ I Iberian Congress on Medicinal Biotechnology, 27. https://paginas.ess.ipp.pt/ebtm/2018/3EBtM_BookOfAbstracts.pdf