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Advisor(s)
Abstract(s)
Currently, the evaluation of biomarkers HER-2 and ER is critical for targeting therapy for breast cancer and is performed by experienced pathologists, which takes time and causes a certain interobserver variability. The use of histological slide scanners coupled with the application of software for immunoexpression quantification can be profitable in pathological laboratories routine. This study aims to compare the quantification of HER-2 and ER immunoexpression employing automatic algorithms, using as standard the evaluation performed by a pathologist.
Description
Keywords
Breast cancer Biomarkers Digital pathology Immunoexpression
Citation
Lopes, J., Silva, S., Monteiro, J., Pinto, I. M., & Silva, R. A. (2021). Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer. Coimbra Health School abstract supplement of Annual Meeting 2021; European Journal of Public Health, 31, ii23–ii24. https://doi.org/10.1093/eurpub/ckab120.073
Publisher
OXFORD Academic