Publicação
Integrating PET for tumour hypoxia in radiotherapy planning: Insights from Portuguese radiotherapy and nuclear medicine technologists
| dc.contributor.author | Sousa, Ruben Diogo Oliveira | |
| dc.contributor.author | Faria, Brígida Mónica | |
| dc.contributor.author | Bravo, Isabel | |
| dc.contributor.author | Costa, Pedro | |
| dc.contributor.author | Costa, Pedro | |
| dc.contributor.author | Faria, Brigida Monica | |
| dc.date.accessioned | 2026-01-28T11:57:30Z | |
| dc.date.available | 2026-01-28T11:57:30Z | |
| dc.date.issued | 2026-02 | |
| dc.description.abstract | In the era of personalised medicine, tumour hypoxia (TH) is critical in radiotherapy (RT) response due to its role in tumour resistance. Positron Emission Tomography (PET) enables non-invasive assessment of TH and supports heterogeneous dose-escalation to hypoxic sub-volumes, improving treatment efficacy. This study explores Nuclear Medicine Technologists (NMT) and Radiotherapy Technologists (RTT) perceptions of PET-based TH (PET-TH) assessment and implementation in RT planning in Portugal. We conducted an observational cross-sectional survey of RTTs and NMTs currently working in Portuguese healthcare institutions. Statistical tests were used to assess associations and compare distributions using IBM® SPSS®. A total of 66 participants, 57 (86.4 %) females, with a mean age of 33.68 (±8.13) years, were included: 23 (34.8 %) NMTs and 43 (65.2 %) RTTs. While 65.2 % of NMT departments had PET scans with RT-compatible settings, only 8.7 % had performed PET-TH studies. Among RTTs, 88.4 % reported that their treatment planning systems were compatible with PET/CT fusion, yet only 9.3 % had used PET in RT planning. RTTs received more training in TH (p = 0.006) and rated their knowledge higher than NMTs (p = 0.042). Greater professional experience and higher perceived knowledge were associated with better performance on evaluation items (p = 0.027; p = 0.037). Regardless of institution type, 92.4 % expressed interest in interprofessional collaboration to support individualised planning. The assessed departments possess infrastructures for PET-TH integration, yet clinical implementation remains limited. Knowledge and professional experience are associated with competency. Targeted training for Technologists and interdisciplinary workflows may improve PET-TH adoption. Addressing knowledge and workflow could facilitate PET integration into RT planning and potentially enhance treatment outcomes. Future efforts should focus on interdisciplinary collaboration. | eng |
| dc.identifier.citation | Oliveira-Sousa, R., Faria, B. M., Bravo, I., & Costa, P. (2026). Integrating PET for tumour hypoxia in radiotherapy planning: Insights from Portuguese radiotherapy and nuclear medicine technologists. Radiography, 32(2), 103270. https://doi.org/10.1016/j.radi.2025.103270 | |
| dc.identifier.doi | 10.1016/j.radi.2025.103270 | |
| dc.identifier.eissn | 1532-2831 | |
| dc.identifier.issn | 1078-8174 | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/31751 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | Elsevier | |
| dc.relation.hasversion | https://www.sciencedirect.com/science/article/pii/S1078817425004146?via%3Dihub | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Positron emission tomography | |
| dc.subject | Radiotherapy | |
| dc.subject | Tumour hypoxia | |
| dc.subject | Precision medicine | |
| dc.subject | Professional development | |
| dc.title | Integrating PET for tumour hypoxia in radiotherapy planning: Insights from Portuguese radiotherapy and nuclear medicine technologists | eng |
| dc.type | research article | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 2 | |
| oaire.citation.title | Radiography | |
| oaire.citation.volume | 32 | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
| person.familyName | Costa | |
| person.familyName | Faria | |
| person.givenName | Pedro | |
| person.givenName | Brigida Monica | |
| person.identifier | R-000-T1F | |
| person.identifier.ciencia-id | DA11-C4E7-D9D1 | |
| person.identifier.ciencia-id | 0D1F-FB5E-55E4 | |
| person.identifier.orcid | 0000-0002-9280-2750 | |
| person.identifier.orcid | 0000-0003-2102-3407 | |
| person.identifier.rid | C-6649-2012 | |
| person.identifier.scopus-author-id | 6506476517 | |
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| relation.isAuthorOfPublication | 85832a40-7ef9-431a-be0c-78b45ebbae86 | |
| relation.isAuthorOfPublication.latestForDiscovery | 4cb1e0d1-44c9-4475-a28a-9efce8220cf4 |