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Taraxacum spp. in vitro and in vivo anticancer activity – a review

2022-11-08Journal article Restricted access
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dc.contributor.authorOliveira, Ana Isabel
dc.contributor.authorPinho, Cláudia
dc.contributor.authorQuintela Vieira, Ana Filipa
dc.contributor.authorSilva, Regina
dc.contributor.authorCruz, Agostinho
dc.date.accessioned2022-12-13T18:12:25Z
dc.date.available2022-12-13T18:12:25Z
dc.date.issued2022-11-08
dc.description.abstractCancer is one of the major causes of death universally. Conventional chemotherapeutic agents are associated with severe side effects which limit their general acceptability and leads to a search for alternative efficient and safe options. Plants have been used for centuries as medicinal agents in the treatment of several diseases, including cancer. Dandelion is a plant of the genus Taraxacum and a member of the Asteraceae family with worldwide distribution. It has been used in traditional medicine for the treatment of various disorders, such as gastrointestinal and kidney diseases, dyspepsia, Diabetes mellitus, pneumonia and cancer. The present review aims to provide a comprehensive summary of the main biologically active compounds of dandelion, gathering and describing the information about its anticancer activity. Several in vitro and in vivo studies have demonstrated the cytotoxic ability of Taraxacum species, which can be possibly explained by the complexity and diversity of its phytochemical profile. Therefore, dandelion may have the potential to become an effective chemotherapeutic agent despite the need for further studies.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationOliveira, A. I., Pinho, C., Vieira, F. Q., Silva, R., & Cruz, A. (2022). Taraxacum spp. In vitro and in vivo anticancer activity – A review. Journal of Herbal Medicine, 36, 100612. https://doi.org/10.1016/j.hermed.2022.100612pt_PT
dc.identifier.doi10.1016/j.hermed.2022.100612pt_PT
dc.identifier.eissn2210-8041
dc.identifier.issn2210-8033
dc.identifier.urihttp://hdl.handle.net/10400.22/21192
dc.language.isoengpt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S2210803322000811pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectTaraxacumpt_PT
dc.subjectDandelionpt_PT
dc.subjectCancer therapypt_PT
dc.subjectPhytochemicalspt_PT
dc.titleTaraxacum spp. in vitro and in vivo anticancer activity – a reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage8pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleJournal of Herbal Medicinept_PT
oaire.citation.volume36pt_PT
person.familyNameOliveira
person.familyNamePinho
person.familyNameQuintela Vieira
person.familyNameCruz
person.givenNameAna Isabel
person.givenNameCláudia
person.givenNameAna Filipa
person.givenNameAgostinho
person.identifier.ciencia-id9212-F501-E9EF
person.identifier.ciencia-id8B1B-A0D9-B6E4
person.identifier.orcid0000-0003-4420-6476
person.identifier.orcid0000-0002-3157-3712
person.identifier.orcid0000-0003-0130-7664
person.identifier.orcid0000-0002-1157-8196
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4b3fe293-2740-469f-97d3-99d0b107b5e0
relation.isAuthorOfPublication01c994b8-cb20-43a8-947c-d2b978283944
relation.isAuthorOfPublication47123d10-a0ed-47cc-a751-721489a13446
relation.isAuthorOfPublicationd7ec3c5d-b3e0-4e34-8e24-4d1588876120
relation.isAuthorOfPublication.latestForDiscovery47123d10-a0ed-47cc-a751-721489a13446

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