Repository logo
 
Publication

Nonthermal high-pressure microalgae extracts: A new source of natural ingredients for cosmetics

2024-07Journal article Embargoed access
Simple item page
dc.contributor.authorGarcia, Mónica P.
dc.contributor.authorRegueiras, Ana
dc.contributor.authorLopes, Graciliana
dc.contributor.authorMatos, Gabriela
dc.contributor.authorSilva, Lucília P. da
dc.contributor.authorCerqueira, Mariana T.
dc.contributor.authorCardoso, Helena
dc.contributor.authorCorreia, Nádia
dc.contributor.authorSaraiva, Jorge A.
dc.contributor.authorSilva, Joana L.
dc.contributor.authorMartins, Rosário
dc.contributor.authorMarques, Alexandra P.
dc.date.accessioned2024-07-03T15:00:27Z
dc.date.embargo2026-07
dc.date.issued2024-07
dc.description.abstractMicroalgae are one of the most prominent sources of ingredients for the cosmetic industry not only due to their diversity but, importantly, due to the low environmental impact in production and extraction. A sustainable extraction process requires the use of effective and environmentally friendly solvents that guarantee an extract with a relevant content and in high yields. In this work, Chlorella vulgaris, Nannochloropsis oceanica, Tetraselmis chui, Chlorococcum amblystomatis and Phaeodactylum tricornutum microalgae species grown in tubular photobioreactors were used to validate a high-pressure extraction (HPE) method. Extraction yields up to 57 % were obtained depending on the used solvent (water, ethanol, or acetone). The extracts were then characterized regarding their phytochemical composition (total phenolic, protein, chlorophylls content, and chlorophyll a). Aqueous extracts showed high protein content (6–51 μg/mg biomass), while ethanolic and acetone extracts showed high amounts of phenolic compounds (0.0007–0.03 μg/mg biomass). The levels of photosynthetic pigments (0.1–11 μg/mg biomass) associated with antioxidant and anti-inflammatory properties were higher when extracted using ethanol and high-pressures. Chlorella vulgaris aqueous extracts presented higher protein content while Nannochloropsis oceanica and Tetraselmis chui ethanolic extracts presented higher amounts of photosynthetic pigments. The effect of the extracts over the metabolic activity of primary human dermal fibroblasts, keratinocytes, melanocytes, and adipocytes was dependent on both microalgae species and cell type. In adipocytes and fibroblasts, extracts presented an IC50 > 500 μg/mL, except for the one of Phaeodactylum tricornutum in fibroblasts (IC50 < 150 μg/mL). In contrast, the IC50 was below 500 μg/mL for most of the extracts in keratinocytes and melanocytes. Overall, extracts of sustainably-grown microalgae obtained by a high-pressure method are a promising source of natural ingredients for cosmeceutical applications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGarcia, M. P., Regueiras, A., Lopes, G., Matos, G., da Silva, L. P., Cerqueira, M. T., Cardoso, H., Correia, N., Saraiva, J. A., Silva, J. L., Martins, R., & Marques, A. P. (2024). Nonthermal high-pressure microalgae extracts: A new source of natural ingredients for cosmetics. Algal Research, 81, 103591. https://doi.org/10.1016/j.algal.2024.103591pt_PT
dc.identifier.doi10.1016/j.algal.2024.103591pt_PT
dc.identifier.issn2211-9264
dc.identifier.urihttp://hdl.handle.net/10400.22/25731
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationThe authors are also grateful to financial support from FCT to CIIMAR (UIDB/04423/2020 and UIDP/04423/2020), to University of Aveiro, to Allmicroalgae (PhD fellowship 2020.07229.BD), from FCT/MCTES (LA/P/0008/2020 DOI 10.54499/LA/P/0008/2020, UIDP/50006/2020 DOI 10.54499/UIDP/50006/2020 and UIDB/50006/2020 DOI 10.54499/UIDB/50006/2020), through national funds, from FCT under the Scientific Employment Stimulus – Individual Call (CEEC Individual) – 2020.01541.CEECIND/CP1600/CT0024 to LPdS, and from FCT/MCTES (Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) and ESF (European Social Fund) through NORTE 2020 (Programa Operacional Região Norte) to Gabriela Matos for her PhD grant ref. 2021.07139.BD.pt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S2211926424002030?via%3Dihubpt_PT
dc.subjectMicroalgaept_PT
dc.subjectCosmeticspt_PT
dc.subjectHigh-pressure extractionpt_PT
dc.subjectSustainabilitypt_PT
dc.titleNonthermal high-pressure microalgae extracts: A new source of natural ingredients for cosmeticspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleAlgal Researchpt_PT
oaire.citation.volume81pt_PT
person.familyNameMartins
person.givenNameRosario
person.identifier.ciencia-idA919-DB40-EF10
person.identifier.orcid0000-0002-9882-4651
person.identifier.scopus-author-id21834368700
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication82a7c349-c88e-450f-adc7-3331d69149cf
relation.isAuthorOfPublication.latestForDiscovery82a7c349-c88e-450f-adc7-3331d69149cf

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ART_Rosário Martins.pdf
Size:
5.53 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ESS - CISA - Artigos
ESS - CM - Artigos