Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study

Tavares, Diana; Madeira, Maria H.; Marques, Inês P.; Santos, Torcato; Santos, Ana Rita; Lobo, Conceição; Cunha-Vaz, José

http://hdl.handle.net/10400.22/19066

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Abstract(s)

Diabetic Retinopathy (DR)is a frequent complication of DiabetesMellitus (DM) andthe main cause of vision loss in the working population in western countries. Diabetic Retinopathy has always been considered a microvascular disease, but it has been suggested that neurodegeneration is also associated with this complex pathology[1], although there is evidence indicating that the neurodegenerative process may progress independently[2]. To evaluate this potential association, we have examined the progression of neurodegeneration over a 5-year period of follow-up (considering thinning of ganglion cell + inner plexiform retinal layers (GCL+IPL) in individuals with type 2 diabetes (T2D) and nonproliferative DR) and explored whetheritis associated with microaneurysmturnover (MAT), diseaselevel at baseline and severity progression.

Keywords

Diabetic retinopathy Mixed models Neurodegeneration

URI

http://hdl.handle.net/10400.22/19066

Citation

Tavares, D., Madeira, M., Marques, I., Santos, T., Santos, A., Lobo, C., & Cunha-Vaz, J. (2021). Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study. Journal of Statistics on Health Decision, 3(1), 36-37. https://doi.org/10.34624/jshd.v3i1.24805