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Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study

2021-06Journal article Open access
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dc.contributor.authorTavares, Diana
dc.contributor.authorMadeira, Maria H.
dc.contributor.authorMarques, Inês P.
dc.contributor.authorSantos, Torcato
dc.contributor.authorSantos, Ana Rita
dc.contributor.authorLobo, Conceição
dc.contributor.authorCunha-Vaz, José
dc.date.accessioned2021-12-14T10:45:20Z
dc.date.available2021-12-14T10:45:20Z
dc.date.issued2021-06
dc.description.abstractDiabetic Retinopathy (DR)is a frequent complication of DiabetesMellitus (DM) andthe main cause of vision loss in the working population in western countries. Diabetic Retinopathy has always been considered a microvascular disease, but it has been suggested that neurodegeneration is also associated with this complex pathology[1], although there is evidence indicating that the neurodegenerative process may progress independently[2]. To evaluate this potential association, we have examined the progression of neurodegeneration over a 5-year period of follow-up (considering thinning of ganglion cell + inner plexiform retinal layers (GCL+IPL) in individuals with type 2 diabetes (T2D) and nonproliferative DR) and explored whetheritis associated with microaneurysmturnover (MAT), diseaselevel at baseline and severity progression.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTavares, D., Madeira, M., Marques, I., Santos, T., Santos, A., Lobo, C., & Cunha-Vaz, J. (2021). Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study. Journal of Statistics on Health Decision, 3(1), 36-37. https://doi.org/10.34624/jshd.v3i1.24805pt_PT
dc.identifier.doi10.34624/jshd.v3i1.24805pt_PT
dc.identifier.issn2184-5794
dc.identifier.urihttp://hdl.handle.net/10400.22/19066
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherUniversidade Aveiropt_PT
dc.relation.publisherversionhttps://proa.ua.pt/index.php/jshd/article/view/24805pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectDiabetic retinopathypt_PT
dc.subjectMixed modelspt_PT
dc.subjectNeurodegenerationpt_PT
dc.titleProgression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage37pt_PT
oaire.citation.startPage36pt_PT
oaire.citation.titleJournal of Statistics on Health Decisionpt_PT
oaire.citation.volume3pt_PT
person.familyNameSantos
person.givenNameAna Rita
person.identifier.ciencia-id0911-4138-0C3A
person.identifier.orcid0000-0003-0139-0285
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationd71931b8-d869-4334-993c-ba14ad713f01
relation.isAuthorOfPublication.latestForDiscoveryd71931b8-d869-4334-993c-ba14ad713f01

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