Publication
Electroanalytical study of the antidepressant sertraline
| dc.contributor.author | Nouws, Henri P. A. | |
| dc.contributor.author | Delerue-Matos, Cristina | |
| dc.contributor.author | Barros, Aquiles A. | |
| dc.contributor.author | Rodrigues, José A. | |
| dc.date.accessioned | 2013-11-27T16:34:17Z | |
| dc.date.available | 2013-11-27T16:34:17Z | |
| dc.date.issued | 2005 | |
| dc.description.abstract | Aflowinjection squarewave cathodic stripping voltammetric method has been developed for the determination of sertraline in a pharmaceutical preparation. The method shows linearity between peak current intensity and sertraline concentration for the interval between 0.20×10−6 and 1.20×10−6 mol L−1. Limits of detection and quantification were found to be 1.5×10−7 and 5.0×10−7 mol L−1, respectively. Up to 70 samples per hour can be analysed with a good precision (R.S.D. = 2.5%). The proposed method was successfully applied to the determination of sertraline in a commercial product. In the voltammetric determination of sertraline in flow, a high sample rate is obtained at reduced costs, opening the possibility to compete with the chromatographic methods generally used for this analysis. | por |
| dc.identifier.doi | 10.1016/j.jpba.2005.02.040 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.22/3007 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Elsevier | por |
| dc.relation.ispartofseries | Journal of Pharmaceutical and Biomedical Analysis; Vol.39, Issue 1-2 | |
| dc.relation.publisherversion | http://www.sciencedirect.com/science/article/pii/S0731708505001986# | por |
| dc.subject | Flow injection | por |
| dc.subject | Hanging mercury drop electrode | por |
| dc.subject | Adsorptive stripping voltammetry | por |
| dc.subject | Sertraline | por |
| dc.subject | SSRI | por |
| dc.title | Electroanalytical study of the antidepressant sertraline | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 293 | por |
| oaire.citation.startPage | 290 | por |
| oaire.citation.title | Journal of Pharmaceutical and Biomedical Analysis | por |
| oaire.citation.volume | 39 | por |
| person.familyName | Delerue-Matos | |
| person.givenName | Cristina | |
| person.identifier.ciencia-id | 9A1A-43FB-5C27 | |
| person.identifier.orcid | 0000-0002-3924-776X | |
| person.identifier.rid | D-4990-2013 | |
| person.identifier.scopus-author-id | 6603741848 | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
| relation.isAuthorOfPublication | 09f6a7bd-2f15-42b0-adc5-04bd22210519 | |
| relation.isAuthorOfPublication.latestForDiscovery | 09f6a7bd-2f15-42b0-adc5-04bd22210519 |