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Diffusion MRI outside the brain

dc.contributor.authorNunes, Rita G.
dc.contributor.authorNogueira, Luisa
dc.contributor.authorGaspar, Andreia S.
dc.contributor.authorAdubeiro, Nuno
dc.contributor.authorBrandão, Sofia
dc.date.accessioned2022-05-18T16:05:52Z
dc.date.available2022-05-18T16:05:52Z
dc.date.issued2019-05
dc.description.abstractThis manuscript provides an overview of recent developments in Diffusion-Weighted Imaging (DWI) outside the brain, focusing on liver, breast, prostate, muskuloskeletal (MSK) and cardiac applications. A general introduction to cross-cutting acquisition and image processing challenges is first provided. These often include short T2 relaxation times, the need to image a large field-of-view with the resulting complications in shimming the B0 field and achieving good fat suppression. Some of the strategies developed for dealing with motion, namely cardiac and respiratory motion are described. Specific sections are then presented for each of the aforementioned organs. A motivation for the clinical applicability of DWI is first provided, followed by specific image acquisition and processing considerations. Quantitative imaging is becoming standard in clinical practice, and the Apparent Diffusion Coefficient is routinely estimated in the liver, breast and prostate. Application of alternative signal models in these organs is being explored, including both the Intravoxel Incoherent Motion and Diffusion Kurtosis models. Ongoing efforts are focused on evaluating the potential clinical added value of the extra parameters and on improving their repeatability. MSK and cardiac DWI have shown potential for assessing pathological changes in fiber architecture, but further validation is required to enable application in the clinical setting.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNunes, R.G., Nogueira, L., Gaspar, A.S., Adubeiro, N., Brandão, S. (2019). Diffusion MRI Outside the Brain. In: Bonet-Carne, E., Grussu, F., Ning, L., Sepehrband, F., Tax, C. (eds) Computational Diffusion MRI. MICCAI 2019. Mathematics and Visualization. Springer, Cham. https://doi.org/10.1007/978-3-030-05831-9_19pt_PT
dc.identifier.doi10.1007/978-3-030-05831-9_19pt_PT
dc.identifier.isbn978-3-030-05831-9
dc.identifier.isbn978-3-030-05830-2
dc.identifier.urihttp://hdl.handle.net/10400.22/20540
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.subjectDiffusion-weighted MRIpt_PT
dc.subjectLiverpt_PT
dc.subjectBreastpt_PT
dc.subjectProstatept_PT
dc.subjectMuskuloskeletal systempt_PT
dc.subjectCardiacpt_PT
dc.subjectApplicationspt_PT
dc.titleDiffusion MRI outside the brainpt_PT
dc.typebook part
dspace.entity.typePublication
oaire.citation.endPage249pt_PT
oaire.citation.startPage227pt_PT
oaire.citation.titleComputational Diffusion MRI, MICCAI 2019pt_PT
person.familyNameNogueira
person.familyNameAdubeiro
person.givenNameLuisa
person.givenNameNuno
person.identifier.ciencia-id0119-2885-C797
person.identifier.orcid0000-0002-1291-9490
person.identifier.orcid0000-0001-8657-3288
person.identifier.ridAAC-1663-2021
rcaap.rightsclosedAccesspt_PT
rcaap.typebookPartpt_PT
relation.isAuthorOfPublicationc2991b07-7696-4d2b-ad5d-863790e33130
relation.isAuthorOfPublication35d1aa21-3c2a-4af6-8346-efa61cd513fc
relation.isAuthorOfPublication.latestForDiscoveryc2991b07-7696-4d2b-ad5d-863790e33130

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