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Enhanced detection with prussian blue-based nanocubes: a novel electrochemical biosensor for bovine serum albumin analysis: microfluidic integration

dc.contributor.authorSantos, Andréa dos
dc.contributor.authorOliveira, Daniela
dc.contributor.authorMartins, Gabriela
dc.contributor.authorMoreira, Felismina T.C.
dc.date.accessioned2024-11-08T15:40:18Z
dc.date.available2024-11-08T15:40:18Z
dc.date.issued2024
dc.descriptionThe authors would like to acknowledge the partial support of the Portuguese Foundation for Science and Technology (FCT), through grants UIDB/04730/2020 and UIDP/04730/2020. This study was financed by project IBEROS+ (0072_IBEROS_MAIS_1_E, Interreg-POCTEP 2021-2027).pt_PT
dc.description.abstract(Introduction) Early diagnosis of biomarkers is crucial for optimizing treatments and increasing survival rates. Direct and cost-effective assays are important for point-of-care (PoC) testing. Bovine serum albumin (BSA) monitoring indicates liver and kidney function and aids in the assessment of diseases such as cirrhosis and chronic kidney disease. An innovative electrochemical biosensor was developed in which a platinum electrode was decorated with manganese-based Prussian blue nanocubes (PB-NC). A molecularly imprinted polymer (MIP) was created on the electrode surface by electropolymerization of phenol in the presence of BSA using cyclic voltammetry (CV). The template was removed with proteinase K and a mixture of methanol and acetic acid. Square wave voltammetry (SWV) characterized the performance of the sensor, which exhibited high sensitivity and allowed detection of BSA at nanomolar levels.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.citationSantos, A., Oliveira, D., Martins, G. & Moreira, F.T.C. (2024, Jun. 14). Enhanced detection with prussian blue-based nanocubes: a novel electrochemical biosensor for bovine serum albumin analysis: microfluidic integration [Poster presentation]. IBEROS+ - II Jornadas do Instituto de Biofabricação em Rede para o Envelhecimento Saudável, Porto, Portugalpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/26371
dc.language.isoengpt_PT
dc.relationCenter for Innovation in Industrial Engineering and Technology
dc.relationCenter for Innovation in Industrial Engineering and Technology
dc.subjectBiomarkerspt_PT
dc.subjectSurvival ratespt_PT
dc.subjectElectrochemical biosensorpt_PT
dc.titleEnhanced detection with prussian blue-based nanocubes: a novel electrochemical biosensor for bovine serum albumin analysis: microfluidic integrationpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleCenter for Innovation in Industrial Engineering and Technology
oaire.awardTitleCenter for Innovation in Industrial Engineering and Technology
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04730%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04730%2F2020/PT
oaire.citation.conferencePlacePorto, Portugalpt_PT
oaire.citation.titleIBEROS+ - II Jornadas do Instituto de Biofabricação em Rede para o Envelhecimento Saudávelpt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMartins
person.familyNameMoreira
person.givenNameGabriela
person.givenNameFelismina
person.identifier1589429
person.identifier.ciencia-id0219-87C9-5E5B
person.identifier.ciencia-idC917-6A46-A270
person.identifier.orcid0000-0001-6739-1526
person.identifier.orcid0000-0003-4237-8952
person.identifier.scopus-author-id55918092100
person.identifier.scopus-author-id23486193000
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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relation.isAuthorOfPublication9c13153d-a73a-49ff-b7f6-c9733bc6725e
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