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Bioaccessibility and changes on cylindrospermopsin concentration in edible mussels with storage and processing time

dc.contributor.authorFreitas, Marisa
dc.contributor.authorAzevedo, Joana
dc.contributor.authorCarvalho, António Paulo
dc.contributor.authorMendes, Vera M.
dc.contributor.authorManadas, Bruno
dc.contributor.authorCampos, Alexandre
dc.contributor.authorVasconcelos, Vitor
dc.date.accessioned2017-01-10T10:49:52Z
dc.date.available2017-01-10T10:49:52Z
dc.date.issued2016
dc.description.abstractThe alkaloid cylindrospermopsin has been recognized of increased concern due to the global expansion of its main producer, Cylindrospermopsis raciborskii. Previous studies have shown that bivalves can accumulate high levels of cylindrospermopsin. Based on the potential for human health risks, a provisional tolerable daily intake of 0.03 μg/kg-body weight has been recommended. However, the human exposure assessment has been based on the cylindrospermopsin concentration in raw food items. Thus, this study aimed to assess the changes on cylindrospermopsin concentration in edible mussels with storage and processing time as well as cylindrospermopsin bioaccessibility. Mussels, (Mytilus galloprovincialis) fed cylindrospermopsin-producing C. raciborskii, were subjected to the treatments and then analyzed by LC-MS/MS. Mussels stored frozen allowed a significantly higher recovery of cylindrospermopsin (52.5% in 48 h and 57.7% in one week). The cooking treatments did not produce significant differences in cylindrospermopsin concentration in the mussel matrices (flesh), however, cylindrospermopsin was found in the cooking water, suggesting that heat processing can be used to reduce the availability of cylindrospermopsin. The in vitro digestion considerably decreased the cylindrospermopsin availability in uncooked and steamed mussels, highlighting the importance in integrating the bioaccessibility of cylindrospermopsinin in the human health risk assessment.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/j.foodcont.2015.06.025pt_PT
dc.identifier.issn0956-7135
dc.identifier.urihttp://hdl.handle.net/10400.22/9174
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0956713515300542pt_PT
dc.subjectBioaccessibilitypt_PT
dc.subjectCylindrospermopsinpt_PT
dc.subjectFood storagept_PT
dc.subjectFood processingpt_PT
dc.subjectMytilus galloprovincialispt_PT
dc.subjectIn vitro digestionpt_PT
dc.titleBioaccessibility and changes on cylindrospermopsin concentration in edible mussels with storage and processing timept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage574pt_PT
oaire.citation.startPage567pt_PT
oaire.citation.titleFood Controlpt_PT
oaire.citation.volume59pt_PT
person.familyNameFreitas
person.givenNameMarisa
person.identifier.ciencia-id131C-AD64-7E5F
person.identifier.orcid0000-0003-1886-4942
person.identifier.scopus-author-id7102366695
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationee4b4693-5911-46e5-9247-129bafa5a864
relation.isAuthorOfPublication.latestForDiscoveryee4b4693-5911-46e5-9247-129bafa5a864

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