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Exploring the bioactive potential of Gracilaria gracilis: An extraction optimization study using response surface methodology

dc.contributor.authorNeves, Cátia
dc.contributor.authorMorais, Stephanie
dc.contributor.authorVale, Tiago
dc.contributor.authorSoares, Cristina
dc.contributor.authorGrosso, Clara
dc.contributor.authorDomingues, Valentina F.
dc.contributor.authorVieira, Mónica
dc.contributor.authorDelerue-Matos, Cristina
dc.contributor.authorVieira, Mónica
dc.date.accessioned2026-01-07T17:07:08Z
dc.date.available2026-01-07T17:07:08Z
dc.date.issued2023-10-14
dc.description.abstractThe extraction of bioactive compounds from the seaweed Gracilaria gracilis was optimized for food use using a Response Surface Methodology. Two designs, Central Composite Face-centered (CCD) and Box-Behnken (BBD) assessed the effects of extraction time, temperature, and seaweed-to-solvent ratio using water as the solvent. The extraction yield was assessed by Total Phenolic Content (TPC). BBD’s best model was a Reduced Quadratic (R2 = 0.9356), predicting 3.336 mg GAE/L at 74 °C in 1.4 h with a 1:75 ratio. CCD’s top was Reduced Cubic (R2 = 0.9091), forecasting 4.278 mg GAE/L at 46 °C in 1.1 h, the same ratio. The actual obtained TPC values were 4.35 mg GAE/L for BBD and 4.25 mg GAE/L for CCD.eng
dc.description.sponsorship“BLUE BIOECONOMY INNOVATION PACT” (Project Nº C644915664-00000026)
dc.identifier.citationNeves, C., Morais, S., Vale, T., Soares, C., Grosso, C., Domingues, V. F., Vieira, M., & Delerue-Matos, C. (2023). Exploring the bioactive potential of Gracilaria gracilis: An extraction optimization study using response surface methodology. The 4th International Electronic Conference on Foods - Biology and Life Sciences Forum, 26, 13. https://doi.org/10.3390/Foods2023-15026
dc.identifier.doi10.3390/Foods2023-15026
dc.identifier.urihttp://hdl.handle.net/10400.22/31412
dc.language.isoeng
dc.peerreviewedn/a
dc.publisherMDPI
dc.relationREQUIMTE/LAQV—UIDB/50006/2020 and UIDP/50006/2020
dc.relation.hasversionhttps://www.mdpi.com/2673-9976/26/1/13
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectAlgae
dc.subjectExtraction optimization
dc.subjectTotal phenolic compounds (TPC)
dc.titleExploring the bioactive potential of Gracilaria gracilis: An extraction optimization study using response surface methodologyeng
dc.typeconference paper
dspace.entity.typePublication
oaire.citation.conferenceDate2023-10
oaire.citation.issue1
oaire.citation.titleThe 4th International Electronic Conference on Foods - Biology and Life Sciences Forum
oaire.citation.volume26
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameVieira
person.givenNameMónica
person.identifier.orcid0000-0002-9614-9031
person.identifier.ridD-8977-2016
person.identifier.scopus-author-id24464652500
relation.isAuthorOfPublication55587c4b-3df0-4ff1-bade-587420940ecd
relation.isAuthorOfPublication.latestForDiscovery55587c4b-3df0-4ff1-bade-587420940ecd

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