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Cytotoxicity of the soil fungus Pisolithus tinctorius spores against cancer cells – a potential source of anticancer drugs

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Cancer is one of the major causes of death worldwide being the search for new anticancer drugs essential for the treatment of this disease. The sporocarps of the soil fungus Pisolithus tinctorius contain pisosterol, a triterpene that has been shown to have antitumor activity against some cancer cell lines. Nevertheless, no studies have focused on the anticancer potential of other structures such as spores, and so the anticancer potential of P. tinctorius, remains largely unknown.

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Alves, R., Fernandes, J., Preto, M., Oliveira, R. S., & Martins, R. (2015). Cytotoxicity of the soil fungus Pisolithus tinctorius spores against cancer cells – a potential source of anticancer drugs. In R. A. Silva, P. Baylina, F. Q. Vieira, C. Barrias, M. Rubim, T. Coelho, C. Prudêncio, & Â. Jesus (Eds.), II Congresso Internacional da Saúde Gaia Porto: Livro de Resumos (pp. 60). Escola Superior de Tecnologia da Saúde do Instituto Politécnico do Porto.

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ESTSP-IPP

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