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2D:4D digit ratio is associated with cognitive decline but not frailty in community-dwelling older adults

2017Journal article Open access
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dc.contributor.authorGonçalves, Celina
dc.contributor.authorCoelho, Tiago
dc.contributor.authorMachado, Sérgio
dc.contributor.authorRocha, Nuno
dc.date.accessioned2019-02-27T17:36:49Z
dc.date.available2019-02-27T17:36:49Z
dc.date.issued2017
dc.description.abstractObjectives To understand the relation between 2D:4D ratio, frailty, and cognitive decline in community-dwelling elderly people. Methods A total of 175 community-dwelling elderly people were included. To determine frailty, participants completed the Tilburg Frailty Indicator (TFI) and the Survey of Health, Ageing and Retirement in Europe (SHARE-FI). Cognitive functioning was determined using the Mini-Mental State Examination (MMSE). 2D and 4D finger lengths of each hand were measured using a scanner. Barthel Index, Lawton, and Brody scale were also completed for each participant to determine the level of daily living functioning. Results We did not find any correlations between 2D:4D ratio and frailty measures. We found a significant correlation between 2D:4D ratio and MMSE scores in the women sampled. Conclusions We cannot ascertain any contribution of prenatal exposure to androgens to the frailty status of community-dwelling elderly people. We found that reduced prenatal exposure to testosterone in women may contribute to the prevention of cognitive decline in elderly womenpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1002/ajhb.23003pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/12922
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/full/10.1002/ajhb.23003pt_PT
dc.title2D:4D digit ratio is associated with cognitive decline but not frailty in community-dwelling older adultspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPagee23003pt_PT
oaire.citation.titleAmerican Journal of Human Biologypt_PT
person.familyNameCoelho
person.familyNameRocha
person.givenNameTiago
person.givenNameNuno
person.identifier188655
person.identifier192266
person.identifier.ciencia-idB417-8E58-EF75
person.identifier.ciencia-idAE16-A494-5F8B
person.identifier.orcid0000-0001-7847-2401
person.identifier.orcid0000-0002-3139-2786
person.identifier.ridJJC-7415-2023
person.identifier.ridM-9821-2013
person.identifier.scopus-author-id56583916600
person.identifier.scopus-author-id32867975300
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication7c814c96-7746-4d89-ab01-ed2e4af5ab92
relation.isAuthorOfPublication9e940914-601a-4978-8d5b-74e5ade7ada7
relation.isAuthorOfPublication.latestForDiscovery7c814c96-7746-4d89-ab01-ed2e4af5ab92

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