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Executive Function Impairments in Patients with Depression

dc.contributor.authorAlves, Mariana
dc.contributor.authorYamamoto, Tetsuya
dc.contributor.authorCarrion, Oscar
dc.contributor.authorRocha, Nuno
dc.contributor.authorNardi, António
dc.contributor.authorMachado, Sérgio
dc.contributor.authorCardoso, Adriana
dc.date.accessioned2015-01-09T12:19:14Z
dc.date.available2015-01-09T12:19:14Z
dc.date.issued2014
dc.description.abstractDepression, the most prevalent psychiatric disorder, has a lifelong risk of 20% and is related to high rates of death among the patients. Thus, this study aims to conduct a systematic review of changes in executive functions of adult patients diagnosed with depression. We found 1381 articles; however, only 28 were selected and recovered. The inclusion criteria was the assessment of executive functions with at least one neuropsychological test, and articles that evaluated primarily adult individuals with depression, without comparison to other psychiatric disorders. Although most of the studies (25 out of 28 analyzed) have shown deficits in some executive subcomponents, these findings are not conclusive because they used different parameters of assessment. Moreover, many variables were not controlled, such as the different subtypes of the disorder, the high level of severity, comorbidity and the use of drugs. Most studies showed different deficits in executive functions in depressed patients, but further longitudinal studies are needed in order to confirm these findings.por
dc.identifier.urihttp://hdl.handle.net/10400.22/5370
dc.language.isoporpor
dc.relation.publisherversionhttps://www.ingentaconnect.com/content/ben/cnsnddt/2014/00000013/00000006/art00015pt_PT
dc.subjectCognitive impairment
dc.subjectDepression
dc.subjectDrugs
dc.subjectExecutive functions
dc.subjectNeuropsychological assessment
dc.titleExecutive Function Impairments in Patients with Depressionpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1040por
oaire.citation.startPage1026por
oaire.citation.titleCNS and Neurological Disorders - Drug Targetspor
oaire.citation.volume13por
person.familyNameRocha
person.givenNameNuno
person.identifier192266
person.identifier.ciencia-idAE16-A494-5F8B
person.identifier.orcid0000-0002-3139-2786
person.identifier.ridM-9821-2013
person.identifier.scopus-author-id32867975300
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication9e940914-601a-4978-8d5b-74e5ade7ada7
relation.isAuthorOfPublication.latestForDiscovery9e940914-601a-4978-8d5b-74e5ade7ada7

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