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Sensitive ratiometric imprinted hydrogel for the detection of matrix metalloproteinase 7 (MMP7) biomarker

2024Conference object Open access
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dc.contributor.authorPiloto, Ana Margarida L.
dc.contributor.authorRibeiro, David S.M.
dc.contributor.authorSantos, João L.M.
dc.contributor.authorSales, Goreti
dc.date.accessioned2024-11-08T14:07:58Z
dc.date.available2024-11-08T14:07:58Z
dc.date.issued2024
dc.description.abstractA dual-emissive fluorescent probe has been developed for the sensitive and selective detection of matrix metalloproteinase 7 (MMP7), a protein biomarker associated with pancreatic cancer1,2. The resultant materials were designated as imprinted ratiometric hydrogels (imprinted rHGs). The fluorescence quenching of the imprinted rHGs occurred with increasing concentrations of MMP7, showing linearity in the range [1.49 x 10-11 – 1.92 x 10-9] g/mL in 1000-fold diluted human serum in PBS 10mM pH 5.8. Overall, the imprinted rHGs developed in this work presented increased selectivity for the MMP7 protein over raw emitting QDs nanoparticles and higher sensitivity comparatively to the non-imprinted rHGs.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.citationPiloto, A.M.L., Ribeiro, D.S.M., Santos, J.L.M., & Sales, G. (2024, Jun. 23-26). Sensitive ratiometric imprinted hydrogel for the detection of matrix metalloproteinase 7 (MMP7) biomarker [Abstract]. RICI X - 10th Iberian Meeting on Colloids and Interfaces, Coimbra, Portugalpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/26366
dc.language.isoengpt_PT
dc.relationNovos sitemas óticos biomiméticos para o seguimento de biomarcadores de cancro
dc.relationCellulose bio-nanocomposites as test-strips for protein cancer biomarkers
dc.relationCenter for Innovation in Industrial Engineering and Technology
dc.relationCenter for Innovation in Industrial Engineering and Technology
dc.titleSensitive ratiometric imprinted hydrogel for the detection of matrix metalloproteinase 7 (MMP7) biomarkerpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleNovos sitemas óticos biomiméticos para o seguimento de biomarcadores de cancro
oaire.awardTitleCellulose bio-nanocomposites as test-strips for protein cancer biomarkers
oaire.awardTitleCenter for Innovation in Industrial Engineering and Technology
oaire.awardTitleCenter for Innovation in Industrial Engineering and Technology
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/Concurso de Projetos de I&D em Todos os Domínios Científicos - 2022/2022.07897.PTDC/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F116067%2F2016/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04730%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04730%2F2020/PT
oaire.citation.conferencePlaceCoimbra, Portugalpt_PT
oaire.citation.titleRICI X - 10th Iberian Meeting on Colloids and Interfacespt_PT
oaire.fundingStreamConcurso de Projetos de I&D em Todos os Domínios Científicos - 2022
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameL. Piloto Cerqueira
person.familyNameRibeiro
person.familyNameSantos
person.familyNameFerreira Sales
person.givenNameAna Margarida
person.givenNameDavid
person.givenNameJoão L.M.
person.givenNameMaria Goreti
person.identifierR-000-722
person.identifier826970
person.identifier.ciencia-idAD1C-28E2-F781
person.identifier.ciencia-id7F12-6515-F349
person.identifier.ciencia-idDF1F-6EE7-FD43
person.identifier.ciencia-idE31F-1630-42BB
person.identifier.orcid0000-0002-2374-2467
person.identifier.orcid0000-0001-7879-0143
person.identifier.orcid0000-0003-3947-6025
person.identifier.orcid0000-0001-9936-7336
person.identifier.ridG-5788-2018
person.identifier.ridD-5818-2013
person.identifier.ridD-5923-2013
person.identifier.ridK-9199-2013
person.identifier.scopus-author-id8527885100
person.identifier.scopus-author-id8227151300
person.identifier.scopus-author-id25628662600
person.identifier.scopus-author-id7005174717
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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