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Advisor(s)
Abstract(s)
Adipose tissue is no longer considered to be an inert tissue that stores fat. This
tissue is capable of expanding to accommodate increased lipids through hypertrophy
of existing adipocytes and by initiating differentiation of pre-adipocytes.
Adipose tissue metabolism exerts an impact on whole-body metabolism. As an
endocrine organ, adipose tissue is responsible for the synthesis and secretion
of several hormones. These are active in a range of processes, such as control
of nutritional intake (leptin, angiotensin), control of sensitivity to insulin and
inflammatory process mediators (tumor necrosis factor α (TNF-α), interleukin-6
(IL-6), resistin, visfatin, adiponectin, among others) and pathways (plasminogen
activator inhibitor 1 (PAI-1) and acylation stimulating protein (ASP) for example).
This paper reviews some of the biochemical and metabolic aspects of adipose
tissue and its relationship to inflammatory disease and insulin resistance.
Description
Keywords
Adipose tissue Adipocytes Adipokines
Citation
Publisher
Termedia & Banach