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Advisor(s)
Abstract(s)
Melanoma is the most aggressive skin cancer characterized by a high metastatic potential and poor survival
rate, leading to major morbidity/mortality. Overweight, obesity and diet composition have been identified as
risk factors for many types of cancers. However, there are cancers where obesity is associated with favorable
outcomes and this has been coined the “obesity paradox”.
Preliminary data obtained by our research group disclosed paradoxical findings unveiling that obesity act as
a two-edged sword in melanoma: potentiating primary tumor growth, and vascularity/angiogenesis, but at the
same time decrease metastatic potential, thus preventing secondary tumor growth.
In this exploratory research project, we propose to further explore and deepen the impact that fat-rich diets
and obesity partake in melanoma etiology
Description
Keywords
Citation
Correia, J., Costa, R., Prudêncio, C., Soares, R., & Coelho, P. (2022). Fattymess: Fat diet-induced obesity in melanoma metastasis. Atas Do I Encontro de Investigação Da Escola Superior de Saúde Do Politécnico Do Porto, Pp. 3-8, ESS | P. PORTO Edições, 141–148. https://doi.org/10.26537/recipp-23959
Publisher
ESS | P. PORTO Edições