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The role of molecular imaging in modern drug development

dc.contributor.authorCunha, Lídia
dc.contributor.authorSzigeti, Krisztián
dc.contributor.authorMathé, Domokos
dc.contributor.authorMetello, Luís F.
dc.date.accessioned2015-05-20T15:14:18Z
dc.date.available2015-05-20T15:14:18Z
dc.date.issued2014
dc.description.abstractDrug development represents a highly complex, inefficient and costly process. Over the past decade, the widespread use of nuclear imaging, owing to its functional and molecular nature, has proven to be a determinant in improving the efficiency in selecting the candidate drugs that should either be abandoned or moved forward into clinical trials. This helps not only with the development of safer and effective drugs but also with the shortening of time-to-market. The modern concept and future trends concerning molecular imaging will assumedly be hybrid or multimodality imaging, including combinations between high sensitivity and functional (molecular) modalities with high spatial resolution and morphological techniques.por
dc.identifier.doi10.1016/j.drudis.2014.01.003
dc.identifier.urihttp://hdl.handle.net/10400.22/6069
dc.language.isoengpor
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S135964461400004X#por
dc.titleThe role of molecular imaging in modern drug developmentpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage948por
oaire.citation.startPage936por
oaire.citation.titleDrug Discovery Todaypor
oaire.citation.volume19por
person.familyNameCunha
person.givenNameLídia
person.identifier.orcid0000-0002-9260-8093
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicationed51e8c5-a1c2-40e6-b976-57af77446e1b
relation.isAuthorOfPublication.latestForDiscoveryed51e8c5-a1c2-40e6-b976-57af77446e1b

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