Publication
Antimicrobial activity of food-isolated fungi extracts
| dc.contributor.author | Ferreira, Diogo | |
| dc.contributor.author | Areal-Hermida, Lara | |
| dc.contributor.author | Baylina, Pilar | |
| dc.contributor.author | Fernandes, Rúben | |
| dc.contributor.author | Sieiro, Carmen | |
| dc.date.accessioned | 2024-07-09T13:08:41Z | |
| dc.date.available | 2024-07-09T13:08:41Z | |
| dc.date.issued | 2023-11 | |
| dc.description.abstract | One major source for drug discovery are microbial metabolites. Fungi, renowned for their ability to produce an array of broad and diverse secondary metabolites, due to their extensive dispersion and diversity, offer a rich resource for drug discovery. Antibiotic resistance is a major concern. Rapid increase of resistant bacteria worldwide, dampens antibiotic efficiency, burdens healthcare services and increase morbidity and mortality. Antibiotic misuse and lack of new drug development are the main responsible for this health crisis. So, the creation of fungal libraries to find and study new compounds is essential to tackle the rising of antimicrobial resistance and continue with industrial efforts of drug discovery and production. Isolation from chestnuts, chestnut flour and sunflower seeds allowed us to obtain a collection of 165 fungal isolates. Bioactivity of fungal extracts were screened against different antibiotic resistant bacteria. Bacteria grown overnight, adjusted to 1.5 x 108 CFU/mL was exposed to fungal extracts, at a concentration of 100 μg/mL for 24 hours and inhibition rates were calculated. Several extracts showed activity against antimicrobial resistant bacteria and further studies should be made in order to find if new molecules could be responsible for our fungi antimicrobial activity. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Ferreira, D., Areal-Hermida, L., Baylina, P., Fernandes, R., & Sieiro, C. (2023). Antimicrobial activity of food-isolated fungi extracts. Em R. P. Rocha & J. L. Faria (Eds.), Livro de Resumos do XXVII Encontro Luso-Galego de Química (p. 42). Sociedade Portuguesa de Química. | pt_PT |
| dc.identifier.isbn | 978-989-8124-40-1 | |
| dc.identifier.isbn | 978-989-8124-39-5 | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/25750 | |
| dc.language.iso | eng | pt_PT |
| dc.publisher | Sociedade Portuguesa de Química | pt_PT |
| dc.relation | This work is being funded by research grant PORTIC/LABMI/BI72021/02 through project BIOTECH4HEALTH from Instituto Politécnico do Porto and it was done during the mobility Program IACOBUS. | pt_PT |
| dc.relation.publisherversion | https://xxviilgq.events.chemistry.pt/pt/book-of-abstracts | pt_PT |
| dc.subject | Microbial metabolites | pt_PT |
| dc.subject | Drug discovery | pt_PT |
| dc.title | Antimicrobial activity of food-isolated fungi extracts | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Porto | pt_PT |
| oaire.citation.startPage | 42 | pt_PT |
| oaire.citation.title | Livro de Resumos do XXVII Encontro Luso-Galego de Química | pt_PT |
| person.familyName | Ferreira | |
| person.familyName | BAYLINA MACHADO | |
| person.givenName | Diogo | |
| person.givenName | PILAR | |
| person.identifier.ciencia-id | 4418-B544-ACCE | |
| person.identifier.ciencia-id | 1419-F23D-4920 | |
| person.identifier.orcid | 0000-0002-2765-0586 | |
| person.identifier.orcid | 0000-0002-3740-862X | |
| person.identifier.rid | B-5134-2010 | |
| person.identifier.scopus-author-id | 56534079700 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
| relation.isAuthorOfPublication | f73f13d7-af7d-42d5-a828-fbe678f18d70 | |
| relation.isAuthorOfPublication | b1482a24-d9d8-419d-af68-6df1a75afb3f | |
| relation.isAuthorOfPublication.latestForDiscovery | b1482a24-d9d8-419d-af68-6df1a75afb3f |