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Auditory event-related potentials in children with benign epilepsy with centro-temporal spikes

dc.contributor.authorTomé, David
dc.contributor.authorSampaio, Mafalda
dc.contributor.authorMendes-Ribeiro, José
dc.contributor.authorBarbosa, Fernando
dc.contributor.authorMarques-Teixeira, Joao
dc.date.accessioned2015-02-19T12:52:55Z
dc.date.available2015-02-19T12:52:55Z
dc.date.issued2014
dc.description.abstractBenign focal epilepsy in childhood with centro-temporal spikes (BECTS) is one of the most common forms of idiopathic epilepsy, with onset from age 3 to 14 years. Although the prognosis for children with BECTS is excellent, some studies have revealed neuropsychological deficits in many domains, including language. Auditory event-related potentials (AERPs) reflect activation of different neuronal populations and are suggested to contribute to the evaluation of auditory discrimination (N1), attention allocation and phonological categorization (N2), and echoic memory (mismatch negativity – MMN). The scarce existing literature about this theme motivated the present study, which aims to investigate and document the existing AERP changes in a group of children with BECTS. AERPs were recorded, during the day, to pure and vocal tones and in a conventional auditory oddball paradigm in five children with BECTS (aged 8–12; mean = 10 years; male = 5) and in six gender and age-matched controls. Results revealed high amplitude of AERPs for the group of children with BECTS with a slight latency delay more pronounced in fronto-central electrodes. Children with BECTS may have abnormal central auditory processing, reflected by electrophysiological measures such as AERPs. In advance, AERPs seem a good tool to detect and reliably reveal cortical excitability in children with typical BECTS.por
dc.identifier.citationTomé, D., Sampaio, M., Mendes-Ribeiro, J., Barbosa, F., & Marques-Teixeira, J. (2014). Auditory event-related potentials in children with benign epilepsy with centro-temporal spikes. Epilepsy Research, 108(10), 1945–1949. https://doi.org/10.1016/j.eplepsyres.2014.09.021
dc.identifier.doi10.1016/j.eplepsyres.2014.09.021
dc.identifier.urihttp://hdl.handle.net/10400.22/5622
dc.language.isoporpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relation.ispartofseries10;
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S092012111400254X?via%3Dihubpor
dc.subjectBenign rolandic epilepsypor
dc.subjectN1por
dc.subjectN2bpor
dc.subjectAuditory processingpor
dc.subjectMMNpor
dc.titleAuditory event-related potentials in children with benign epilepsy with centro-temporal spikespor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceScience Directpor
oaire.citation.endPage1949por
oaire.citation.startPage1945por
oaire.citation.titleEpilepsy Researchpor
oaire.citation.volume108por
person.familyNameTomé
person.givenNameDavid
person.identifier472686
person.identifier.ciencia-id5F12-B2B1-B40B
person.identifier.orcid0000-0002-1824-1019
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicatione787e2b5-3ea1-4ca0-8a70-576058d54f8e
relation.isAuthorOfPublication.latestForDiscoverye787e2b5-3ea1-4ca0-8a70-576058d54f8e

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