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Intraplacental Choriocarcinoma: Rare or Underdiagnosed? Report of 2 Cases Diagnosed after an Incomplete Miscarriage and a Preterm Spontaneous Vaginal Delivery

dc.contributor.authorCaldas, Rita Ferraz
dc.contributor.authorOliveira, Paula
dc.contributor.authorRodrigues, Cátia
dc.contributor.authorReis, Inês
dc.contributor.authorScigliano, Horácio
dc.contributor.authorNogueira, Rosete
dc.contributor.authorAraújo, Célia
dc.contributor.authorFerreira, Soledade
dc.date.accessioned2019-05-17T16:27:22Z
dc.date.available2019-05-17T16:27:22Z
dc.date.issued2017
dc.description.abstractIntraplacental choriocarcinoma is a rare malignant tumor diagnosed after an abortion, an ectopic pregnancy, or a term or preterm pregnancy or following the diagnosis of a hydatidiform mole. During pregnancy, it may be more common than reported, as most patients are asymptomatic and placental choriocarcinomas are usually inconspicuous macroscopically and are often mistaken for an infarct. Based upon a case study methodology, we describe 2 cases of intraplacental choriocarcinoma: the first case was identified in the product of a uterine curettage following an incomplete miscarriage and the second in one of the placentas of a bichorionic twin pregnancy. Maternal investigation did not reveal evidence of metastatic disease and neither did the infants' one in the second case. The two cases underwent maternal surveillance with serum hCG and remained disease-free until the present. In conclusion, intraplacental choriocarcinoma is easily underdiagnosed but with current treatment, even in the presence of metastasis, the prognosis is excellent. A routine microscopic examination of all the placentas and products of miscarriage can increase the real incidence of this entity and consequently improve its management.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCaldas, R. F., Oliveira, P., Rodrigues, C., Reis, I., Scigliano, H., Nogueira, R., Araújo, C., & Ferreira, S. (2017). Intraplacental Choriocarcinoma: Rare or Underdiagnosed? Report of 2 Cases Diagnosed after an Incomplete Miscarriage and a Preterm Spontaneous Vaginal Delivery. Case Reports in Medicine, 2017, e7892980. https://doi.org/10.1155/2017/7892980
dc.identifier.doi10.1155/2017/7892980pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/13731
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relation.publisherversionhttps://www.hindawi.com/journals/crim/2017/7892980/pt_PT
dc.subjectPlacental histologicalpt_PT
dc.subjectPregnancypt_PT
dc.subjectIntraplacental choriocarcinomapt_PT
dc.titleIntraplacental Choriocarcinoma: Rare or Underdiagnosed? Report of 2 Cases Diagnosed after an Incomplete Miscarriage and a Preterm Spontaneous Vaginal Deliverypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage4pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleCase Reports in Medicinept_PT
oaire.citation.volume2017pt_PT
person.familyNameRodrigues
person.givenNameCátia
person.identifier.orcid0000-0003-3639-3419
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationa072bc84-8464-446d-92a9-ec5f8f4558d3
relation.isAuthorOfPublication.latestForDiscoverya072bc84-8464-446d-92a9-ec5f8f4558d3

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