Repository logo
 
Publication

Presence of pharmaceuticals in the Lis river (Portugal): Sources, fate and seasonal variation

2016Journal article Restricted access
Simple item page
dc.contributor.authorPaíga, Paula
dc.contributor.authorSantos, Lúcia H.M.L.M.
dc.contributor.authorRamos, Sandra
dc.contributor.authorJorge, Sandra
dc.contributor.authorSilva, Jaime Gabriel
dc.contributor.authorDelerue-Matos, Cristina
dc.date.accessioned2017-01-12T10:43:50Z
dc.date.embargo2116
dc.date.issued2016
dc.description.abstractThe occurrence of 33 pharmaceuticals and metaboliteswas evaluated along the Lis river and in the influents and effluents of twowastewater treatment plants (WWTPs) located along the river. Results indicate that pharmaceuticals, such as ibuprofen, ketoprofen, carbamazepine and fluoxetine, and the metabolite salicylic acid are widespread along the Lis river, showing 100% of detection frequency, at levels up to 1.3 μg L–1. The number of molecules detected increased along the river, with 11 molecules in the source, 15 upstreamWWTP 1, 16 downstreamWWTP 1 and upstreamWWTP 2 and 19 downstream WWTP 2. The highest concentrations were often found downstream near the river mouth. Different possible sources of contamination of the Lis river were identified, namelyWWTP effluents, untreated wastewaters and livestock production. Nevertheless, the discharge of WWTP effluents appeared to be the most pronounced, given that, in general, it was noticed an increase in the concentration of pharmaceuticals downstream of the WWTPs. WWTP effluents contributed with a total mass load of pharmaceuticals into the Lis river between 470 and 2317 mg/d/1000 inhabitants. Non-steroidal anti-inflammatory drugs/analgesics were the therapeutic groupwith a high contribution to the total mass load of pharmaceuticals entering the Lis river, followed by psychiatric drugs and antibiotics. No seasonal variation was observed for the detected concentrations of pharmaceuticals. At the levels detected in the Lis river, sulfamethoxazole, clarithromycin, azithromycin and ibuprofen showed to have potential risk for aquatic organisms. These findings show that further studies embracing different environmental compartments (water, sediment and biota) are needed, in order to evaluate the partition/distribution of pharmaceuticals, their metabolites and transformation products in the environment aswell as to predict their possible impact to non-target organisms and, in a last instance, to human health.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/j.scitotenv.2016.08.089pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/9234
dc.language.isoengpt_PT
dc.publisherElsevierpt_PT
dc.relation.ispartofseriesScience of The Total Environment;Vol. 573
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S004896971631782Xpt_PT
dc.subjectPharmaceuticalspt_PT
dc.subjectMetabolitespt_PT
dc.subjectLis riverpt_PT
dc.subjectWastewaterspt_PT
dc.subjectSources of pollutionpt_PT
dc.subjectRisk assessmentpt_PT
dc.titlePresence of pharmaceuticals in the Lis river (Portugal): Sources, fate and seasonal variationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage177pt_PT
oaire.citation.startPage164pt_PT
oaire.citation.titleScience of the Total Environmentpt_PT
oaire.citation.volume573pt_PT
person.familyNamePaíga
person.familyNameDelerue-Matos
person.givenNamePaula
person.givenNameCristina
person.identifier1668889
person.identifier.ciencia-id331A-5D6A-D3C8
person.identifier.ciencia-id9A1A-43FB-5C27
person.identifier.orcid0000-0002-9593-1355
person.identifier.orcid0000-0002-3924-776X
person.identifier.ridQ-4930-2018
person.identifier.ridD-4990-2013
person.identifier.scopus-author-id6506638953
person.identifier.scopus-author-id6603741848
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4a0677dc-0b54-4831-aa9a-4a73f0df911d
relation.isAuthorOfPublication09f6a7bd-2f15-42b0-adc5-04bd22210519
relation.isAuthorOfPublication.latestForDiscovery09f6a7bd-2f15-42b0-adc5-04bd22210519

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ART_MatosCristina_GRAQ_2016_13.pdf
Size:
1.5 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ISEP – GRAQ – Artigos