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Advisor(s)
Abstract(s)
Um dos factores que contribui para a baixa sensibilidade da citologia urinária é a fixação em etanol. Neste trabalho foi avaliada a citomorfologia e as características tintoriais de lavados vesicais fixados pelo FineFIX® ou pelo RCL2® comparativamente aos fixados pelo etanol. A análise dos achados microscópicos revelou que as preparações fixadas pelo RCL2® apresentam qualidade inferior (p=0,001), enquanto as fixadas pelo FineFIX® apresentam qualidade semelhante às fixadas pelo etanol (p=0,204). Relativamente às características nucleares, o FineFIX® providencia qualidade superior ao etanol (p=0,027). O FineFIX® é um potencial fixador citológico por aumentar o detalhe nuclear, característica importante para o diagnóstico.
One of the factors that contribute to the low sensitivity of the urinary cytology is fixation by ethanol. We evaluated the morphology and cytological dyeing features of bladder washings fixed by FineFIX® or by RCL2® compared to fixed by ethanol. The analysis of microscopic findings showed that preparations fixed by RCL2® present lower quality (p=0,001), while preparations fixed by FineFIX® present quality similar to those fixed by ethanol (p=0,204). With respect to nuclear characteristics, the FineFIX® provides higher quality than ethanol (p=0,027). The FineFIX® is a potential fixative for cytology by increase the nuclear detail, an important feature for diagnosis.
One of the factors that contribute to the low sensitivity of the urinary cytology is fixation by ethanol. We evaluated the morphology and cytological dyeing features of bladder washings fixed by FineFIX® or by RCL2® compared to fixed by ethanol. The analysis of microscopic findings showed that preparations fixed by RCL2® present lower quality (p=0,001), while preparations fixed by FineFIX® present quality similar to those fixed by ethanol (p=0,204). With respect to nuclear characteristics, the FineFIX® provides higher quality than ethanol (p=0,027). The FineFIX® is a potential fixative for cytology by increase the nuclear detail, an important feature for diagnosis.
Description
Keywords
Citologia urinária Sensibilidade Etanol FineFIX® RCL2® Urine cytology Sensitivity Ethanol
Citation
Publisher
Instituto Politécnico do Porto. Escola Superior de Tecnologia da Saúde do Porto - Politema