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Spectroscopic detection of pigments in tissues: correlation with tissue aging and cancer development

2022Review Restricted access
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dc.contributor.authorOliveira, Luís M.
dc.contributor.authorGoncalves, T. M.
dc.contributor.authorBotelho, A. R.
dc.contributor.authorMartins, I. S.
dc.contributor.authorSilva, H. F.
dc.contributor.authorCarneiro, I.
dc.contributor.authorCarvalho, S.
dc.contributor.authorHenrique, R.
dc.contributor.authorTuchin, V. V.
dc.date.accessioned2023-02-16T11:20:44Z
dc.date.embargo2035-12-31
dc.date.issued2022
dc.description.abstractThe direct calculation of the absorption coefficient spectra of various tissues from spectral measurements allowed to retrieve the contents of melanin and lipofuscin. In the rabbit brain cortex, 1.8 times higher melanin content is explained by the neuron degeneration process. Similar melanin and lipofuscin contents were found in the rabbit pancreas as a result of the tissue aging process. The conversion of 83 % of the melanin in the human normal kidney into lipofuscin in the cancer kidney indicates that lipofuscin can be considered a kidney cancer marker in humans.pt_PT
dc.description.sponsorshipThis research was supported by the Portuguese grant FCT -UIDB/04 730/2020. VVT was supported by the RF Government grant 075-15-2021-615.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1109/ICLO54117.2022.9839939pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/22344
dc.language.isoengpt_PT
dc.publisherIEEEpt_PT
dc.relationUIDB/04 730/2020pt_PT
dc.relation075-15-2021-615pt_PT
dc.relation.publisherversionhttps://ieeexplore.ieee.org/author/37089478320pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAbsorption coefficient spectrumpt_PT
dc.subjectMelaninpt_PT
dc.subjectLipofuscinpt_PT
dc.subjectTissue agingpt_PT
dc.subjectCancer developmentpt_PT
dc.titleSpectroscopic detection of pigments in tissues: correlation with tissue aging and cancer developmentpt_PT
dc.typereview
dspace.entity.typePublication
oaire.citation.endPage1pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleInternational Conference Laser Optics (ICLO)pt_PT
person.familyNameOliveira
person.givenNameLuís
person.identifier414820
person.identifier.ciencia-idC312-F342-BD23
person.identifier.orcid0000-0003-0667-3428
person.identifier.ridB-7198-2017
person.identifier.scopus-author-id55853723900
rcaap.rightsclosedAccesspt_PT
rcaap.typereviewpt_PT
relation.isAuthorOfPublication4e2de4d7-142a-400f-8dbf-cd0ff9551093
relation.isAuthorOfPublication.latestForDiscovery4e2de4d7-142a-400f-8dbf-cd0ff9551093

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