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Biological effects of low doses of ionizing radiation are not yet consistently studied and documented. In this context, more advanced and complex biological models should be applied to obtain relevant data.
Recognizing the need to evolve and develop advanced biological models, in order to try overcome as much as possible known limitations and difficulties of the current monolayer cellular models, as well as the increasing difficulties to use advanced biological models, our group has been working to develop distinct advanced biological alternative models, namely three-dimensional cell cultures.