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The impact of war on asthma, a systematic review and meta-analysis: An EAACI task force report

2026-01Artigo de investigação Acesso embargado
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dc.contributor.authorRufo, João Cavaleiro
dc.contributor.authorPaciência, Inês
dc.contributor.authorJutel, Marek
dc.contributor.authorMoreira, André
dc.contributor.authorAnnesi-Maesano, Isabella
dc.contributor.authorSuojalehto, Hille
dc.contributor.authorZemelka-Wiącek, Magdalena
dc.contributor.authorTrikamjee, Thulja
dc.contributor.authorDemir, Semra
dc.contributor.authorEguíluz-Gracia, Ibon
dc.contributor.authorCarvalho, Daniela
dc.contributor.authorBackland, Anaïs
dc.contributor.authorLawson, Josh
dc.contributor.authorCavaleiro Rufo, João
dc.date.accessioned2026-01-23T11:16:42Z
dc.date.available2026-01-23T11:16:42Z
dc.date.issued2026-01
dc.description.abstractWartime events have been followed by an increase in asthma prevalence, which is believed to result from a combination of environmental hazards and psychological trauma. This systematic review and meta-analysis aimed to investigate this relationship by pooling available data on various wartime exposures, such as occupational, environmental, and psychological factors. MEDLINE, Scopus, and Cochrane databases were searched for articles that measure the effect of war-related exposures on asthma. Risk of bias was assessed using the Effective Public Health Practice Project tool. The retrieved effects were then used to fit meta-analytical models. A total of 48 studies, corresponding to 90 effect measures, were included. War-related post-traumatic stress disorder showed the strongest association with asthma outcomes (OR [95% CI]=2.25 [1.04, 4.89]), followed by experiencing at least one life-threatening event (1.96 [1.18, 3.26]) and depression (1.56 [1.02, 2.37]). Although environmental exposures were also associated with an increased asthma risk in subgroup analysis (1.64 [1.32, 2.04]), this effect was mitigated when psychological variables were included in the models. The study's results show that wartime events and conflicts may increase asthma prevalence and outcomes associated with asthma. The management of asthma symptoms, lung function, and mental health seems fundamental in individuals who have experienced psychological trauma in war zones.eng
dc.identifier.citationCavaleiro Rufo, J., Paciência, I., Jutel, M., Moreira, A., Annesi-Maesano, I., Suojalehto, H., Zemelka-Wiącek, M., Trikamjee, T., Demir, S., Eguíluz-Gracia, I., Carvalho, D., Backland, A., & Lawson, J. (2026). The Impact of War on Asthma, a Systematic Review and Meta-Analysis: An EAACI Task Force Report. Allergy, 81(1), 69–83. https://doi.org/10.1111/all.70038
dc.identifier.doi10.1111/all.70038
dc.identifier.eissn1398-9995
dc.identifier.issn0105-4538
dc.identifier.urihttp://hdl.handle.net/10400.22/31635
dc.language.isoeng
dc.peerreviewedyes
dc.publisherWiley
dc.relation2020.01350.CEECIND
dc.relation.hasversionhttps://onlinelibrary.wiley.com/doi/10.1111/all.70038
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectEnvironment
dc.subjectExposure
dc.subjectkinetic warfare
dc.subjectPollution
dc.subjectPost-traumatic stress disorder
dc.subjectTrauma
dc.titleThe impact of war on asthma, a systematic review and meta-analysis: An EAACI task force reportpor
dc.typeresearch article
dspace.entity.typePublication
oaire.citation.endPage83
oaire.citation.issue1
oaire.citation.startPage69
oaire.citation.titleAllergy
oaire.citation.volume81
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameCavaleiro Rufo
person.givenNameJoão
person.identifierR-00F-QED
person.identifier.ciencia-id0F14-AD98-862F
person.identifier.orcid0000-0003-1175-242X
person.identifier.ridK-7994-2013
person.identifier.scopus-author-id56549851500
relation.isAuthorOfPublication762b2c6e-6710-4061-bc68-74084b460ccf
relation.isAuthorOfPublication.latestForDiscovery762b2c6e-6710-4061-bc68-74084b460ccf

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