ESS - PTE - Medicina Nuclear
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- The role of molecuclar imaging in modern drug developmentPublication . Cunha, Lídia Alexandra dos SantosDrug development represents a highly complex, inefficient and costly process. Over the last decade, the widespread use of nuclear imaging, due to its functional and molecular nature, has proven to be determinant in improving the efficiency on selecting the candidate drugs that should be abandoned or move forward to clinical. This reflects not only into the development of safer and effective drugs, but also the shortening of time-to-market. The modern concept and future trends concerning molecular imaging is assumedly hybrid or multimodality imaging, including combinations between high sensitivity and functional (molecular) modalities with high spatial resolution and morphological techniques
- CYCLOTech - an innovative approach for the reliable production of 99mTc - technetiumPublication . Metello, Luís F.CYCLOTech is a high-tech Project, related with an innovative method for direct production of a radioactive pharmaceutical, used in excess of 85% of 35 Million Nuclear Medicine procedures done yearly, worldwide, representing globally more than 3 Billion Euros. The CYCLOTech team has developed an innovative proprietary methodology based on the use of Cyclotron Centers, formally identified as the Clients (actually, there are around 450 of this Centers in function worldwide), to directly produce and deliver the radiopharmaceutical to the final users, at the Hospitals and other Health Institutions (estimating at around 25.000, worldwide). The investment still need to finish Research and Technological Development (RTD), Industrial, Regulatory and Intellectual Property Rights (IPR) issues and allow the introduction in the Market is 4,35 M€, with a Payback of 3 years, with an Investment Return Rate (IRR) of 81,7% and a Net Present Value (NPV) of 60.620.525€ (in 2020).