ISEP - GRAQ - Grupo de Reacção de Análises Químicas
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O GRAQ é uma equipa pluridisciplinar de investigadores cuja missão é a investigação no domínio da Engenharia Química e da Química Verde, contribuindo para a criação, aplicação e divulgação de conhecimento e promover a inovação. O GRAQ está integrado no Laboratório Associado para a Química Verde - REQUIMTE.
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Browsing ISEP - GRAQ - Grupo de Reacção de Análises Químicas by Subject "1-hydroxypyrene"
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- Polycyclic aromatic hydrocarbons at fire stations: firefighters’ exposure monitoring and biomonitoring, and assessment of the contribution to total internal dosePublication . Oliveira, Marta; Slezakova, Klara; Alves, Maria José; Fernandes, Adília; Teixeira, João Paulo; Delerue-Matos, Cristina; Pereira, Maria Do Carmo; Morais, SimoneThis work characterizes levels of eighteen polycyclic aromatic hydrocarbons (PAHs) in the breathing air zone of firefighters during their regular work shift at eight Portuguese fire stations, and the firefighters' total internal dose by six urinary monohydroxyl metabolites (OH-PAHs). Total PAHs (ΣPAHs) concentrations varied widely (46.4-428ng/m3), mainly due to site specificity (urban/rural) and characteristics (age and layout) of buildings. Airborne PAHs with 2-3 rings were the most abundant (63.9-95.7% ΣPAHs). Similarly, urinary 1-hydroxynaphthalene and 1-hydroxyacenaphthene were the predominant metabolites (66-96% ΣOH-PAHs). Naphthalene contributed the most to carcinogenic ΣPAHs (39.4-78.1%) in majority of firehouses; benzo[a]pyrene, the marker of carcinogenic PAHs, accounted with 1.5-10%. Statistically positive significant correlations (r≥0.733, p≤0.025) were observed between ΣPAHs and urinary ΣOH-PAHs for firefighters of four fire stations suggesting that, at these sites, indoor air was their major exposure source of PAHs. Firefighter's personal exposure to PAHs at Portuguese fire stations were well below the existent occupational exposure limits. Also, the quantified concentrations of post-shift urinary 1-hydroxypyrene in all firefighters were clearly lower than the benchmark level (0.5μmol/mol) recommended by the American Conference of Governmental Industrial Hygienists.
- Polycyclic aromatic hydrocarbons at fire stations: firefighters’exposure monitoring and biomonitoring, and assessment of thecontribution to total internal dosePublication . Oliveira, Marta; Slezakova, Klara; Alves, Maria José; Fernandes, Adília; Teixeira, João Paulo; Delerue-Matos, Cristina; Pereira, Maria do Carmo; Morais, SimoneThis work characterizes levels of eighteen polycyclic aromatic hydrocarbons (PAHs) in the breathing airzone of firefighters during their regular work shift at eight Portuguese fire stations, and the firefighters’total internal dose by six urinary monohydroxyl metabolites (OH-PAHs). Total PAHs ( PAHs) concentra-tions varied widely (46.4–428 ng/m3), mainly due to site specificity (urban/rural) and characteristics (ageand layout) of buildings. Airborne PAHs with 2–3 rings were the most abundant (63.9–95.7% PAHs).Similarly, urinary 1-hydroxynaphthalene and 1-hydroxyacenaphthene were the predominant metabo-lites (66–96% OH-PAHs). Naphthalene contributed the most to carcinogenic PAHs (39.4–78.1%) inmajority of firehouses; benzo[a]pyrene, the marker of carcinogenic PAHs, accounted with 1.5–10%. Statis-tically positive significant correlations (r ≥ 0.733, p ≤ 0.025) were observed between PAHs and urinary OH-PAHs for firefighters of four fire stations suggesting that, at these sites, indoor air was their majorexposure source of PAHs. Firefighter’s personal exposure to PAHs at Portuguese fire stations were wellbelow the existent occupational exposure limits. Also, the quantified concentrations of post-shift uri-nary 1-hydroxypyrene in all firefighters were clearly lower than the benchmark level (0.5 mol/mol)recommended by the American Conference of Governmental Industrial Hygienists.