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- Performance of older adults with and without neurocognitive impairment in the auditory verbal learning test: A systematic review and meta-analysisPublication . Pinto, Joana O.; Barroso, Beatriz C. R.; Peixoto, Bruno; Barbosa, FernandoThis systematic review and meta-analysis aims to synthesize the performance of older adults with and without neurocognitive impairment on the Auditory Verbal Learning Test (AVLT). Specifically, the study seeks to characterize the main features of AVLT versions used in older populations, identify the most frequently assessed psychometric measures and process-based indices, and evaluate how varying levels of neurocognitive impairment affect AVLT scores. This systematic review and meta-analysis was registered in PROSPERO and was conducted following PRISMA 2020 guidelines. A total of 44 studies were included in the review, with 42 included in the meta-analysis. Effect sizes were calculated using Hedges’ g, and moderation and meta-regression analyses were performed. The most reported version was the Rey AVLT with 15-word lists, five learning trials, and a 20-minute delay interval. Process-based indices were underreported. Individuals with neurocognitive disorders (ND) showed significantly lower AVLT scores than healthy controls, with performance worsening in line with ND severity, particularly in delayed recall. Differences in Mini-Mental State Examination scores significantly moderated total learning effect sizes, while age significantly moderated recognition hits. The AVLT, particularly delayed recall, may be a robust tool for distinguishing among normal aging, mild and major ND. However, variability in AVLT administration reduces the diagnostic potential of AVLT. The diagnostic potential of process-based indices has not been explored adequately. Future research should prioritize the standardization of AVLT protocols and the integration of process-based indices to maximize its clinical utility in detecting and tracking neurocognitive decline
- A novel ternary Z-scheme g-C3N4/CQDs/FeVO4 heterojunction for photodegradation of levofloxacin via peroxymonosulfate activationPublication . Yunuo Li, Pengda Han, Dongzhe Zhang, Wenzhi Zhang, Dong-feng Chai, Lijian Meng, Liming Bai, Ming Zhao, Guohua DongCurrently, it is still a significant challenge for photodegradation of the emerging pollutants using g-C3N4 (CN) due to their interior visible light responsibility and rapid recombination of e-/h+. Herein, a novel Z-scheme g-C3N4/CQDs/FeVO4 (CCF) photocatalyst was synthesized by initially preparing hollow tubular g-C3N4/CQDs (CC) and then anchoring FeVO4 on CC. The morphology, structural composition and photoelectrochemical performance of the CCF were investigated by comprehensive characterization such as FT-IR, XPS, XRD, SEM and photoelectrochemical performance tests. The CCF shows superior photodegradation capability toward LFX via activation of peroxymonosulfate (PMS), resulting in a photodegradation efficiency ∼ 97.3 % in the optimal conditions. Apart from the strengthened light responsibility, improved BET specific surface area and porous texture of CCF, the improved photodegradation properties can be ascribed to the formed Z-scheme heterojunction between CC and FeVO4, which can ameliorate the separation efficiency of e-/h+ and accelerate their transfer rate. The addition of CQDs can also serve as a channel for promoting the rapid transfer of photogenerated e-/h+. The photodegradation processes of LFX including generation of reactive oxygen species (ROS) and removal pathways were systematically explored by using radical capturing assays, electron spin resonance (ESR) tests and liquid chromatography-mass spectrometry (LC-MS) techniques. To sum up, this study provides an innovative method for regulating the photocatalytic activity of g-C3N4 via constructing Z-scheme heterostructures and incorporating CQD to degrade emerging contaminants.