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- Prova de conceito da VDA4994 GTL na cadeia de abastecimento da Leonische PortugalPublication . BERNARDINO, JOÃO PEDRO COSTA; Amaral, António Manuel Pereira da SilvaEsta dissertação apresenta o ensaio de implementação e validação, como prova de conceito, da norma VDA 4994 na cadeia de abastecimento da empresa Leonische Portugal. O estudo foi desenvolvido com o objetivo de avaliar a viabilidade da aplicação desta norma no processo logístico de receção de matéria-prima, com especial enfoque numa análise custo-benefício. A investigação foi motivada pelas dificuldades operacionais enfrentadas pela empresa, nomeadamente os constrangimentos causados pelas flutuações de encomendas que influenciam carga de trabalho nas operações de receção. A norma VDA 4994, pertencente ao sistema Global Transport Label, surge como uma solução para melhorar a rastreabilidade, reduzir tarefas manuais e otimizar os fluxos logísticos. A metodologia adotada foi a investigação-ação, permitindo uma abordagem prática e colaborativa em ambiente real, utilizando um fornecedor piloto representativo da cadeia de abastecimento da LP. Foram recolhidos dados quantitativos e qualitativos, como medições cronometradas e análise financeira detalhada, comparando o processo atual com o processo reformulado após o ensaio da implementação da norma. Os resultados demonstram uma redução de 82% nos custos operacionais e uma diminuição de 59% no tempo de execução das tarefas. A eliminação de etapas como a impressão e aplicação de etiquetas contribuiu significativamente para a simplificação do processo. A norma revelou-se eficaz na melhoria da eficiência e na redução da complexidade operacional. Estes resultados confirmam a viabilidade da aplicação da VDA 4994 na Leonische Portugal, respondendo positivamente à questão de investigação e cumprindo os objetivos definidos. Apesar das limitações técnicas identificadas, foram propostas soluções concretas que poderão ser exploradas em trabalhos futuros, reforçando o potencial da norma como ferramenta estratégica na gestão da cadeia de abastecimento.
- Comparative effectiveness of different probiotic delivery methods in oral Candidiasis: A Systematic ReviewPublication . Ashouritoustani, Reihaneh; Pinho, Cláudia; Oliveira, Ana Isabel; Barros, Piedade; Cruz, Agostinho; Cruz, Agostinho; Gonçalves de Barros, Piedade AuroraOral candidiasis, mainly from Candida albicans, affects immunocompromised individuals, the elderly, and denture wearers. Probiotics offer immunomodulatory and microbiota-balancing benefits as potential antifungal alternatives. However, the comparative impact of different probiotic delivery methods remains inadequately explored. This systematic review evaluated the effectiveness of various probiotic delivery methods in reducing Candida colonization and clinical symptoms in oral candidiasis. Following PRISMA 2020 guidelines, a systematic review search across multiple databases included human clinical studies based (Medline, Web of Science, ScienceDirect, and ProQuest) on PICO criteria across all age groups. Outcomes assessed included Candida load, oral microbiota changes, symptom improvement, and disease recurrence. Of 297 articles screened, 10 met inclusion criteria. Delivery methods investigated included lozenges, capsules, yogurt, and cheese. Most studies reported reductions in Candida colony-forming units (CFUs) or prevalence, mainly for C. albicans and for non-albicans species, with probiotics such as Lactobacillus reuteri, L. rhamnosus, L. acidophilus, and Bifidobacterium strains. Some studies reported improved immunological markers, while symptom relief, especially when probiotics were combined with antifungals. Probiotics reduce Candida colonization and symptoms, with potential prolonged effects. They show promise as adjunctive therapies, but standardized, large-scale trials are needed for optimization.
- Impact of telehealth on health outcomes and quality of life in the older adults population: a systematic reviewPublication . Fernandes, Gonçalo; Figueiredo, Teodora; Costa, Elísio; Coelho, Luís; Loyens, DirkBackground: The rapid aging of populations poses major challenges to health and social care systems. Supporting older adults in managing chronic conditions while promoting independence and quality of life requires innovative approaches that extend beyond senior institutional care. Telehealth has emerged as a promising approach to enhance access, continuity, and patient engagement. However, evidence regarding its effectiveness and best practices remains fragmented. Objectives: This systematic review aimed to synthesize current evidence on telehealth interventions for adults aged 65 years and older, focusing on their effects on health outcomes, quality of life, and well-being. Methods: A search across three databases in the last five years identified 37 eligible studies, and data analysis was guided by a comprehensive taxonomy. Interventions were diverse, spanning disease management, rehabilitation, health promotion, clinical decision support, and psychological support. Results: Reported benefits included improved physical function, better chronic disease control, greater health knowledge, and reductions in avoidable hospitalizations. Video-based programs showed greater effectiveness, while telephone-only interventions were most useful when combined with remote monitoring. Adherence was strengthened by professional guidance, caregiver support, and real-time feedback. Discussion: Despite encouraging findings, evidence remains inconsistent regarding quality-of-life outcomes, cost-effectiveness, and scalability across populations, with many studies limited by small samples, short duration, and methodological heterogeneity. Telehealth holds the potential to complement traditional care for older adults across multiple clinical domains, and future research must adopt consistent and comprehensive reporting practices to strengthen decision-making and ensure that this pathway evolves with patients’ needs.