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Browsing by Author "Silva, S."

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  • Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer
    Publication . Lopes, J.; Silva, S.; Monteiro, J.; Pinto, I.M.; Silva, Regina
    Currently, the evaluation of biomarkers HER-2 and ER is critical for targeting therapy for breast cancer and is performed by experienced pathologists, which takes time and causes a certain interobserver variability. The use of histological slide scanners coupled with the application of software for immunoexpression quantification can be profitable in pathological laboratories routine. This study aims to compare the quantification of HER-2 and ER immunoexpression employing automatic algorithms, using as standard the evaluation performed by a pathologist.
    2021-08-03Conference object Open access Show more
  • Influence of physical activity on anxiety levels in pregnancy
    Publication . Santos, Paula Clara; Silva, S.; Vale, S.; Santos, R.; Alves, O.; Moreira, C.; Marques, AI.; Soares-Miranda, L.; Mota, J.
    The aims of this study were twofold. First to evaluate the influence of physical activity (PA) on anxiety levels on pregnancy. Second to analyse the influence of parity and a history of previous miscarriage in PA. In this observational, analytic and cross sectional study, it was used a sample of 100 women, aged 17 to 42 years, from Santo Antonio General Hospital. PA and anxiety were assessed using the Pregnancy Physical Activity Questionnaire (PPAQ) and the Zung Self-Rating Anxiety Scale. It was found that levels of PA were not linearly correlated with the anxiety levels p= 0.144. It was also found an association between PA and parity, whereby multiparous women had higher levels of PA (p=0.020) and between PA and previous miscarriage women with levels of physical activity higher had fewer previous miscarriages (p=0,032). The statistical test used was the Spearman’s ρ and chichisquare. In all tests it was considered a significance level of 0,05. In conclusion, through this study it was not possible to verify that PA during pregnancy is related to anxiety. We concluded that there are only associations between, PA and number of births and PA and a history of previous miscarriage.
    2010-06Conference object Open access Show more