Browsing by Author "Ribeiro, Oscar"
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- Assessing the social dimension of frailty in old age: A systematic reviewPublication . Bessa, Bruno; Ribeiro, Oscar; Coelho, TiagoIntroduction Different concepts of frailty have resulted in different assessment tools covering distinct dimensions. Despite the growing recognition that there is an association between frailty and social factors, there’s a lack of clarity on what is being assessed in terms of “social aspects” of frailty. Objective This paper provides a review of frailty assessment instruments (screening tools and severity measures) with a special focus on their social components. Methods Systematic review of studies published in English between 2001 and March 2018 in the PubMed database using a combination of MeSH Terms and logical operators through inclusion and exclusion criteria. Results A total of 27 assessment tools including at least one social question were identified. Three instruments focuses exclusively on social frailty, whereas the weight of social dimensions in the other instruments ranges between 5% and 43%. Social activities, social support, social network, loneliness and living alone were the social concepts most represented by the social components of the various frailty instruments. Conclusion Social components of frailty vary from instrument to instrument and cover the concepts of social isolation, loneliness, social network, social support and social participation.
- Polypharmacy and drug interactions in older patients with cancer receiving chemotherapy: associated factorsPublication . Ferraz Oliveira, Rita; Oliveira, Ana Isabel; Cruz, Agostinho; Ribeiro, Oscar; Afreixo, Vera; Pimentel, FranciscoPolypharmacy in older adults with cancer receiving chemotherapy leads to increased risks of drug interactions, translating in potential hazardous health outcomes. This study aims to assess the prevalence of polypharmacy, drug–drug interactions (DDIs), and severe-drug interactions (SDIs) in older patients with cancer. Antineoplastic agents (ANAs) involvement and possible risk contexts (comorbidities with cardiac risk, and high-risk medications) were also analysed. ents (ANAs); it was conducted in three hospitals from the north of Portugal. Data collection was obtained using self-reports and medical records. DDIs were identifed and classifed using Micromedex® software. Descriptive and association analyze statistics were performed. Statistical hypothesis tests with p value less than 0.05 were considered signifcant. All statistical procedures and analysis were performed with R version 4.1.3. We enrolled 552 patients. Polypharmacy prevalence was 88.40%; 76.45% and 56.16% of the patients presented with DDIs and SDIs, respectively. SDIs with ANAs were found in 21.20% of the patients. High-risk medications were associated with a higher risk of polypharmacy, DDIs, and SDIs. Polypharmacy and DDIs were higher in patients with hypertension or diabetes. SDIs were higher in patients with diabetes. Polypharmacy, potential DDIs and SDIs were highly prevalent in older adults with cancer. A careful review of the medication administered is necessary to decrease it. These fndings warrant further research to optimize medication in this population and decrease problems related to medication, which may lead to emergency room visits and hospitalisations, compromising patient safety and/or ongoing treatments.