Browsing by Author "Ribeiro, M."
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- Baseline Characterization of Retinal Vascular Disease in Eyes with Mild to Moderate Non Proliferative Diabetic Retinopathy (NPDR) in Diabetes Type 2, Using Novel Non-Invasive Imaging Methods, in a Longitudinal, Prospective and Interventional 2-Year Clinical Study (Cordis)Publication . Ribeiro, M.; Marques, I.P.; Santos, Ana Rita; Coimbra, R.; Santos, T.; Figueira, J.; Cunha-Vaz, J.G.Characterization of retinal microvascular changes occurring in eyes with mild to moderate non proliferative diabetic retinopathy (NPDR), during a period of 2 years using lower than optical normal reflectivity (LOR) ratios obtained with OCT-Leakage. Capillary closure in the superficial and deep retinal vascular layers using OCTAngiography (OCTA) will be also analyzed in eyes that are at risk for developing sight threatening diabetic retinopathy (central involved macular edema (CIME) or proliferative diabetic retinopathy (PDR).
- Nutrient adequacy of Nfuma, the flour from Strychnos Madagascariensis fruitPublication . Ribeiro, M.; Chemane, S.; Pinto, Edgar; Khan, M.; Ferreira, I.M.P.L.V.O.; Casal, S.; Pinho, O.; Viegas, O.African native fruits play a significant role in reducingmicronutrient deficiencies and increasing the income of poor rural communitiesin developing countries. In Mozambique, the fruit of Strychnosmadagascariensis is usually processed into flour, nfuma, and is consumed by local communities during staple food shortage.However, there is practically no data on its nutritional value. Therefore, this study aimed to evaluate the nutritional composition and adequacy of nfuma. Flours were collected from four districts of Mozambique and analyzed using AOAC methods for proximate composition, HPLC for sugars, vitamin E and carotene profiles and ICP-MS and FAAS for minerals. The estimated daily intake of nutrients, as % of EFSA dietary reference values (DRVs), was calculated assuming an average daily consumption of 100 g and 50 g of nfuma for adults and children, respectively. Nfumapresents high content of fat (~27%), fiber (> 6%), sugars (~10%), vitamin E (6.7 to 8.0 mg/100 g) and carotenes (2.2 to 2.6 mg/100 g). Oleic acid was the main fatty acid ofnfuma (~16g/100 g of flour). The mineral composition reveals K (~1200 to 1700 mg/100g) and Mn (~4 mg/100g) as the main macro-mineral and trace element, respectively. Regarding current DRVsfor adults, the consumption of 100 g of nfuma provides 30% of fiber, 27-48% of alpha-linolenic acid, 55-63% of vitamin A and 56-66% of vitamin E. Moreover, nfuma can contribute to the daily intake of Mg, K, and Mn (22 - 26%, 40% and > 100% of DRVs, respectively). Due to its high β-carotene content, the daily consumption of 50 g of nfuma provides 82% of vitamin A DRV for toddlers, representing a promising food-based strategy to alleviate the high prevalence of vitamin A deficiency in Mozambique. This fruit flour stands out for its high fat content, mainly composed by MUFA, delivering vitamin E and carotenes, together with naturally occurring sugars and high fiber content. Its local use to enrich maize-based porridges or to develop healthier new food products deserve to be technologically approached for wider valorization.