Browsing by Author "Rente, Ana Rita"
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- Atividade antioxidante de produtos contendo cogumelos comercializados em PortugalPublication . Rente, Ana Rita; Torres, Beatriz; Oliveira, Ana Isabel; Oliveira, Rita Ferraz; Pinho, CláudiaNos últimos anos, o interesse crescente pela saúde, alimentação e prevenção de doenças, tem levado à procura de alimentos funcionais, por parte da população. Os cogumelos têm atraído a atenção dos consumidores face aos seus benefícios nutricionais e de saúde; à baixa toxicidade; e importante fonte de compostos bioativos. Os cogumelos têm vindo a ser estudados pela sua atividade anticancerígena, imunoestimulante e antioxidante. No entanto, a implementação no mercado de suplementos antioxidantes contendo cogumelos não está ainda completamente explorada com sucesso. Desta forma, o trabalho apresenta como objetivo geral a avaliação in vitro da atividade antioxidante de produtos contendo dois tipos de cogumelos, Cordyceps sinensis e Ganoderma lucidum (Reishi), comercializados em Portugal.
- Safety and efficacy of iota-carrageenan nasal spray in treatment and prevention of the common coldPublication . Bichiri, Diana; Rente, Ana Rita; Jesus, ÂngeloThe common cold is one of the most frequent viral infections in humans. Although benign, its symptoms result in economic burden and can lead to severe or even fatal complications in children, elderly and groups with comorbidities. The main purpose of the treatment is the relief of symptoms; however, the medication is often associated with adverse effects. Iota-carrageenan is a polysaccharide that reveals antiviral activity by binding to viruses, inhibiting its replications and, consequently, its viral propagation. This systematic review of the literature aims to compare the effectiveness of an iota-carrageenan nasal spray to placebo. This systematic review was conducted through research in Cochrane Database, PubMed, Science Direct, SpringerLink, Oxford Journals, Elsevier, ClinicalKey, Wiley Online Library, Embase databases, in order to collect randomized and controlled clinical trials. In total, the research provided four articles regarding clinical trials for comparing iota-carrageenan nasal spray with placebo. The results show it has potent antiviral activity compared to placebo and a favorable safety profile. Although further research is needed, the concept of a physical barrier capable of reducing viral penetration of epithelial cells in the nasal mucosa is appealing, and could lead to alternative approaches, with positive impact on global health