Percorrer por autor "Martins, C."
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- Comparative study of PVD and CVD cutting tools performance in milling of duplex stainless steelPublication . Martinho, R. P.; Silva, F. J. G.; Martins, C.; Lopes, H.The machining process evolution has been accompanied by the improvement of tool performance, being this mainly due to the development of thin coatings, mono and multi-layered, providing the most appropriate set of properties for each machining condition. On the other hand, duplex stainless steels have registered a strong increase in demand, which, in many cases, requires the use of machining processes in order to obtain the final shape accurately. Taking into account these two aspects, this paper aims essentially to evaluate the performance of two cutting inserts with PVD and CVD coatings, used in rough milling operations of duplex stainless steel. The cutting parameters and machining conditions were those recommended by the manufacturer and were kept unchanged in all performed tests. The behavior of the PVD- and CVD-coated cutting tools was assessed using three different facets: (a) surface roughness analysis, (b) tool wear evaluation, and (c) the monitoring of vibration levels produced during each test. CVD (TiN/TiCN/Al2O3)-coated inserts showed very good suitability to be used as tools for roughing milling operations when machining super duplex stainless steels.
- A comunicação em saúde como competência transversal: uma exigência do séc. XXIPublication . Dores, Artemisa Rocha; Sousa, Zita; Barreto, João Francisco; Magalhães, Andreia; Martins, C.; Salgado, Ana IsabelO modelo biopsicossocial implica uma conceção de saúde que redefine o papel dos profissionais de saúde e dos utentes/doentes, requerendo por parte dos profissionais também um conjunto de competências designadas por transversais. De entre essas competências destacamos a comunicação em saúde, pela evidência hoje disponível acerca da sua importância na adesão terapêutica, na adaptação à doença crónica, no controlo da dor ou mesmo na confiança no profissional de saúde.
- CytoPath®Easy processing method validation through cervical self-samplingPublication . Fernandes, Sílvia; Martins, C.; Silva, ReginaLiquid-based cytology is mostly used for the identification of pre-neoplastic and neoplastic cells of cérvix uteri, and many manual and automatic methodologies are available on the market. This study aims to validate a new manual liquid-based processing method - the CytoPath® Easy Kit, for its routine use in some cytology laboratories.
- Determinants of maternal exposure to heavy metals and semi-metals: Focus on diet and lifestylePublication . Guimarães, J.; Bracchi, Isabella; Pinheiro, C.; Vieira, M.I.; Barbosa, M. Oliveira; Almeida, A.; Azevedo, R.; Pinto, Edgar; Pestana, D.; Calhau, C.; Prucha, M. do Carmo; Martins, C.; Dias, C.C.; Azevedo, L.F.R.; Ramalho, C.; Fernandes, Virginia Cruz; Keating, E.; Fernandes, Virgínia; Pinto, EdgarKnowledge on determinants and health risks of toxic metal exposure in pregnancy is scarce in Portugal. This study aims to characterize food and lifestyle determinants of maternal exposure to Lead (Pb), Cadmium (Cd) and Arsenic (As). We included 1111 pregnant women undergoing routine 1sttrimester fetal ultrasound scan between 2018 and 2021 at CHUSJoão (Porto) and Hospital CUF Descobertas (Lisbon), who had single pregnancy and gave informed consent. At this stage, we collected diet and lifestyle information and a random urine sample for Pb, Cd and As quantification by ICP-MS. The majority of the sample had detectable urinary levels of toxic elements (n (%) and median (P25; P75) for Pb, Cd (in ng/g), and As (in μg/ g): 980 (88) and 547.2 (289.1; 975.9), 628 (57) and 142.5 (81.5; 234.9), 1080 (97) and 27.4 (14.9; 51.3), respectively). Cd and As urinary concentrations were positively correlated (r s =0.250, p<0.001). Smoking habits were associated with higher Pb (p=0.034) and Cd (p=0.008) levels and Pb levels had a negative weak correlation with birth head circumference (r s =-0.102; p=0.009). Regarding diet, the frequencies of fish and eggs intake were positively associated with Cd and As levels (p=0.005 and p< 0.001, respectively for fish intake; p=0.030 and p<0.001, respectively, for eggs intake). Women who reported consuming fish or eggs at least four times a week presented median (P25; P75) As levels of 35.2 (21.3; 71.9) or 35.9 (16.8; 57.2) μg/g, respectively. These concentrations exceed the commonly accepted reference range (≥24.0 μg/g), observed in healthy populations. Our results evidence that, in pregnant women, smoking might be a determinant of Pb and Cd exposure and fish and eggs might be relevant determinants of Cd and As exposure. These data stress the need to study the consequences of Pb or As and Cd cumulative exposure on the health of the mother and the offspring.
- Noncompliance to iodine supplementation recommendation is a risk factor for iodine insufficiency in Portuguese pregnant women: results from the IoMum cohortPublication . Matta Coelho, C.; Guimarães, J.; Bracchi, I.; Xavier Moreira, N.; Pinheiro, C.; Ferreira, P.; Pestana, D.; Barreiros Mota, I.; Cortez, A.; Prucha, C.; Martins, C.; Pinto, E.; Almeida, A.; Delerue-Matos, Cristina; Dias, C. C.; Moreira-Rosário, A.; Ribeiro de Azevedo, L. F.; Fernandes, Virgínia; Ramalho, C.; Calhau, C.; Brantsæter, A.-L.; Costa Leite, J.; Keating, E.Purpose After a recommendation for iodine supplementation in pregnancy has been issued in 2013 in Portugal, there were no studies covering iodine status in pregnancy in the country. The aim of this study was to assess iodine status in pregnant women in Porto region and its association with iodine supplementation. Methods A cross-sectional study was conducted at Centro Hospitalar Universitário São João, Porto, from April 2018 to April 2019. Pregnant women attending the 1st trimester ultrasound scan were invited to participate. Exclusion criteria were levothyroxine use, gestational age < 10 and ≥ 14 weeks, non-evolutive pregnancy at recruitment and non-signing of informed consent. Urinary iodine concentration (UIC) was measured in random spot urine by inductively coupled plasma-mass spectrometry. Results Median UIC was 104 μg/L (IQR 62–189) in the overall population (n = 481) of which 19% had UIC < 50 µg/L. Forty three percent (n = 206) were not taking an iodine-containing supplement (ICS) and median UIC values were 146 µg/L (IQR 81–260) and 74 µg/L (IQR 42–113) in ICS users and non-users, respectively (p < 0.001). Not using an ICS was an independent risk factor for iodine insufficiency [adjusted OR (95% CI) = 6.00 (2.74, 13.16); p < 0.001]. Iodised salt use was associated with increased median iodine-to-creatinine ratio (p < 0.014). Conclusions A low compliance to iodine supplementation recommendation in pregnancy accounted for a mild-to-moderately iodine deficiency. Our results evidence the need to support iodine supplementation among pregnant women in countries with low household coverage of iodised salt.
- Noncompliance to iodine supplementation recommendation is a risk factor for iodine insufficiency in portuguese pregnant women: results from the IoMum cohortPublication . Matta Coelho, C.; Guimarães, J.; Bracchi, I.; Xavier Moreira, N.; Pinheiro, C.; Ferreira, P.; Pestana, D.; Barreiros Mota, I.; Cortez, A.; Prucha, C.; Martins, C.; Pinto, E.; Almeida, A.; Delerue‑Matos, C.; C. Dias, C.; Moreira‑Rosário, A.; F. Ribeiro de Azevedo, L.; Cruz Fernandes, V.; Ramalho, C.; Calhau, C.; ‑L. Brantsæter, A.; Costa Leite, J.; Keating, E.After a recommendation for iodine supplementation in pregnancy has been issued in 2013 in Portugal, there were no studies covering iodine status in pregnancy in the country. The aim of this study was to assess iodine status in pregnant women in Porto region and its association with iodine supplementation. A cross-sectional study was conducted at Centro Hospitalar Universitário São João, Porto, from April 2018 to April 2019. Pregnant women attending the 1st trimester ultrasound scan were invited to participate. Exclusion criteria were levothyroxine use, gestational age<10 and≥14 weeks, non-evolutive pregnancy at recruitment and non-signing of informed consent. Urinary iodine concentration (UIC) was measured in random spot urine by inductively coupled plasma-mass spectrometry. Median UIC was 104 μg/L (IQR 62–189) in the overall population (n=481) of which 19% had UIC<50 µg/L. Forty three percent (n=206) were not taking an iodine-containing supplement (ICS) and median UIC values were 146 µg/L (IQR 81–260) and 74 µg/L (IQR 42–113) in ICS users and non-users, respectively (p<0.001). Not using an ICS was an independent risk factor for iodine insufciency [adjusted OR (95% CI)=6.00 (2.74, 13.16); p<0.001]. Iodised salt use was associated with increased median iodine-to-creatinine ratio (p<0.014). A low compliance to iodine supplementation recommendation in pregnancy accounted for a mild-to-moderately iodine defciency. Our results evidence the need to support iodine supplementation among pregnant women in countries with low household coverage of iodised salt.