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- Noncompliance to iodine supplementation recommendation is a risk factor for iodine insufficiency in Portuguese pregnant women: results from the IoMum cohortPublication . Matta Coelho, C.; Guimarães, J.; Bracchi, I.; Xavier Moreira, N.; Pinheiro, C.; Ferreira, P.; Pestana, D.; Barreiros Mota, I.; Cortez, A.; Prucha, C.; Martins, C.; Pinto, E.; Almeida, A.; Delerue-Matos, Cristina; Dias, C. C.; Moreira-Rosário, A.; Ribeiro de Azevedo, L. F.; Fernandes, Virgínia; Ramalho, C.; Calhau, C.; Brantsæter, A.-L.; Costa Leite, J.; Keating, E.Purpose After a recommendation for iodine supplementation in pregnancy has been issued in 2013 in Portugal, there were no studies covering iodine status in pregnancy in the country. The aim of this study was to assess iodine status in pregnant women in Porto region and its association with iodine supplementation. Methods A cross-sectional study was conducted at Centro Hospitalar Universitário São João, Porto, from April 2018 to April 2019. Pregnant women attending the 1st trimester ultrasound scan were invited to participate. Exclusion criteria were levothyroxine use, gestational age < 10 and ≥ 14 weeks, non-evolutive pregnancy at recruitment and non-signing of informed consent. Urinary iodine concentration (UIC) was measured in random spot urine by inductively coupled plasma-mass spectrometry. Results Median UIC was 104 μg/L (IQR 62–189) in the overall population (n = 481) of which 19% had UIC < 50 µg/L. Forty three percent (n = 206) were not taking an iodine-containing supplement (ICS) and median UIC values were 146 µg/L (IQR 81–260) and 74 µg/L (IQR 42–113) in ICS users and non-users, respectively (p < 0.001). Not using an ICS was an independent risk factor for iodine insufficiency [adjusted OR (95% CI) = 6.00 (2.74, 13.16); p < 0.001]. Iodised salt use was associated with increased median iodine-to-creatinine ratio (p < 0.014). Conclusions A low compliance to iodine supplementation recommendation in pregnancy accounted for a mild-to-moderately iodine deficiency. Our results evidence the need to support iodine supplementation among pregnant women in countries with low household coverage of iodised salt.
- Noncompliance to iodine supplementation recommendation is a risk factor for iodine insufficiency in portuguese pregnant women: results from the IoMum cohortPublication . Matta Coelho, C.; Guimarães, J.; Bracchi, I.; Xavier Moreira, N.; Pinheiro, C.; Ferreira, P.; Pestana, D.; Barreiros Mota, I.; Cortez, A.; Prucha, C.; Martins, C.; Pinto, E.; Almeida, A.; Delerue‑Matos, C.; C. Dias, C.; Moreira‑Rosário, A.; F. Ribeiro de Azevedo, L.; Cruz Fernandes, V.; Ramalho, C.; Calhau, C.; ‑L. Brantsæter, A.; Costa Leite, J.; Keating, E.After a recommendation for iodine supplementation in pregnancy has been issued in 2013 in Portugal, there were no studies covering iodine status in pregnancy in the country. The aim of this study was to assess iodine status in pregnant women in Porto region and its association with iodine supplementation. A cross-sectional study was conducted at Centro Hospitalar Universitário São João, Porto, from April 2018 to April 2019. Pregnant women attending the 1st trimester ultrasound scan were invited to participate. Exclusion criteria were levothyroxine use, gestational age<10 and≥14 weeks, non-evolutive pregnancy at recruitment and non-signing of informed consent. Urinary iodine concentration (UIC) was measured in random spot urine by inductively coupled plasma-mass spectrometry. Median UIC was 104 μg/L (IQR 62–189) in the overall population (n=481) of which 19% had UIC<50 µg/L. Forty three percent (n=206) were not taking an iodine-containing supplement (ICS) and median UIC values were 146 µg/L (IQR 81–260) and 74 µg/L (IQR 42–113) in ICS users and non-users, respectively (p<0.001). Not using an ICS was an independent risk factor for iodine insufciency [adjusted OR (95% CI)=6.00 (2.74, 13.16); p<0.001]. Iodised salt use was associated with increased median iodine-to-creatinine ratio (p<0.014). A low compliance to iodine supplementation recommendation in pregnancy accounted for a mild-to-moderately iodine defciency. Our results evidence the need to support iodine supplementation among pregnant women in countries with low household coverage of iodised salt.
- An Experimental Study of Two-way Ranging Optimization in UWB-based Simultaneous Localization and Wall-Mapping SystemsPublication . Li, Kai; Ni, Wei; Wei, Bo; Guizani, MohsenIn this paper, we propose a new ultra-wideband (UWB)-based simultaneous localization and wall-mapping (SLAM) system, which adopts two-way ranging optimization on UWB anchor and tag nodes to track the target's real-time movement in an unknown area. The proposed UWB-based SLAM system captures time difference of arrival (TDoA) of the anchor nodes' signals over a line-of-sight propagation path and reflected paths. The real-time location of the UWB tag is estimated according to the real-time TDoA measurements. To minimize the estimation error resulting from background noise in the two-way ranging, a Least Squares Method is implemented to minimize the estimation error for the localization of a static target, while Kalman Filter is applied for the localization of a mobile target. An experimental testbed is built based on off-the-shelf UWB hardware. Experiments validate that a reflector, e.g., a wall, and the UWB tag can be located according to the two-way ranging measurement. The localization accuracy of the proposed SLAM system is also evaluated, where the difference between the estimated location and the ground truth trajectory is less than 15cm.