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Analysis of choroidal macular thickness in early post-Covid-19 patients

2021-05-05Journal article Open access
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dc.contributor.authorJesus, Jeniffer Domingues de
dc.contributor.authorSoares, Raquel J.
dc.contributor.authorDias, Libânia
dc.contributor.authorVentura, Suzana M.
dc.contributor.authorPedro, João C.
dc.date.accessioned2024-11-25T11:48:11Z
dc.date.available2024-11-25T11:48:11Z
dc.date.issued2021-05-05
dc.description.abstractCorona Virus Disease 2019 (COVID-19) is considered a critical global health challenge. Several investigations have suggested vascular dysfunction caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, but regarding ophthalmic involvement, only few data are available. Our aim was to evaluate the choroidal involvement in post-COVID-19 patients. 40 eyes from 40 patients with previous SARS-CoV-2 infection and 40 eyes from 40 age matched controls were included. Choroidal measurements were made using Enhanced Depth Imaging Optical Coherence Tomography (EDI-OCT) at 13 different locations: at central fovea and at intervals of 500μm to 1500μm away from the fovea in the temporal, nasal, superior and inferior regions. Post-COVID-19 patients showed a significant increase in choroidal thickness compared with the control group for all the regions analyzed (all p <0.01). In the Post-COVID-19 group, the choroid is thickest subfoveally and thinnest 1500μm nasal from fovea. In both groups, the superior and temporal macular choroid has been measured thicker than the inferior and nasal macular choroid, respectively. Our results cautiously suggest that post-COVID-19 patients showed an increase in choroidal thickness compared to control groups. This choroidal thickening may reflect the importance of vascular factors in the pathogenesis of SARS-CoV-2 infection. Keywords: Choroid; COVID-19; Hemodynamic Changes; Ocular Circulation; Retina; SARS-CoV-2pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJesus, J. D. de, Soares, R. J., Dias, L. M., Ventura, S. M., & Pedro, J. C. (2021). Analysis of choroidal macular thickness in early post-Covid-19 patients. Acta Scientific Ophthalmology, 4 (5), 168–174. https://doi.org/10.31080/ASOP.2021.04.0315pt_PT
dc.identifier.doi10.31080/ASOP.2021.04.0315pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/26467
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherActa Scientificpt_PT
dc.relation.publisherversionhttps://actascientific.com/ASOP/pdf/ASOP-04-0315.pdfpt_PT
dc.subjectChoroidpt_PT
dc.subjectCOVID-19pt_PT
dc.subjectHemodynamic changespt_PT
dc.subjectOcular circulationpt_PT
dc.subjectRetinapt_PT
dc.subjectSARS-CoV-2pt_PT
dc.titleAnalysis of choroidal macular thickness in early post-Covid-19 patientspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage174pt_PT
oaire.citation.startPage168pt_PT
oaire.citation.titleActa Scientific Ophthalmologypt_PT
oaire.citation.volume4 Issue 5pt_PT
person.familyNameDias
person.givenNameLibânia
person.identifier.ciencia-idA815-A9B2-C84A
person.identifier.orcid0000-0001-6918-4598
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione58d2159-c518-4d7b-b38d-1436f7d62528
relation.isAuthorOfPublication.latestForDiscoverye58d2159-c518-4d7b-b38d-1436f7d62528

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