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Assessment of the effectiveness of allergic rhinitis medications using a target trial emulation approach based on mobile health data

dc.contributor.authorAmaral, Rita
dc.contributor.authorBousquet, Jean
dc.contributor.authorAmaral, Rita
dc.date.accessioned2026-06-22T15:00:01Z
dc.date.available2026-06-22T15:00:01Z
dc.date.issued2025-11-09
dc.description.abstractRandomised controlled trials (RCTs) are the paradigm for questions on causal inference but often face challenges in generalisability due to strict eligibility criteria. In allergic rhinitis (AR), this limitation is particularly relevant, with RCTs on AR displaying an overrepresentation of patients with severe disease and not providing sufficiently detailed information on the impact of comorbidities on treatment effectiveness. Mobile health (mHealth) applications provide an opportunity to collect large-scale patient-reported data that can complement traditional trial evidence and broaden our understanding of treatment effectiveness in routine care. However, to adequately use mHealth data for that purpose, approaches to adequately deal with confounding must be applied.por
dc.identifier.citationLourenço-Silva, N., Sousa-Pinto, B., Bognanni, A., Martini, M., Ordak, M., Paoletti, G., Gil-Mata, S., Amaral, R., Bedbrook, A., Bonadonna, P., Brussino, L., Canonica, G. W., Coutinho-Almeida, J., Cruz, A. A., Czarlewski, W., Dykewicz, M., Giovannini, M., Gemicioglu, B., Ivancevich, J. C., … Vieira, R. J. (2026). Assessment of the Effectiveness of Allergic Rhinitis Medications Using a Target Trial Emulation Approach Based on Mobile Health Data. Clinical & Experimental Allergy, 56(2), 176–179. https://doi.org/10.1111/cea.70173
dc.identifier.doi10.1111/cea.70173
dc.identifier.eissn1365-2222
dc.identifier.issn0954-7894
dc.identifier.urihttp://hdl.handle.net/10400.22/32504
dc.language.isoeng
dc.peerreviewedyes
dc.publisherWiley
dc.relation.hasversionhttps://onlinelibrary.wiley.com/doi/10.1111/cea.70173
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleAssessment of the effectiveness of allergic rhinitis medications using a target trial emulation approach based on mobile health datapor
dc.typeletter
dspace.entity.typePublication
oaire.citation.issue2
oaire.citation.titleClinical & Experimental Allergy
oaire.citation.volume56
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameAmaral
person.givenNameRita
person.identifierR-00H-83K
person.identifier.ciencia-id1A1E-751F-50F0
person.identifier.orcid0000-0002-0233-830X
person.identifier.ridE-5535-2017
person.identifier.scopus-author-id56067841600
relation.isAuthorOfPublication790fdd33-acdb-4dfe-88dc-38538486c9b3
relation.isAuthorOfPublication.latestForDiscovery790fdd33-acdb-4dfe-88dc-38538486c9b3

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