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Analyzing multiple outcomes: is it really worth the use of multivariate linear regression?

dc.contributor.authorOliveira, Rosa
dc.contributor.authorTeixeira-Pinto, Armando
dc.date.accessioned2016-02-02T10:26:10Z
dc.date.available2016-02-02T10:26:10Z
dc.date.issued2015
dc.description.abstractIn health related research it is common to have multiple outcomes of interest in a single study. These outcomes are often analysed separately, ignoring the correlation between them. One would expect that a multivariate approach would be a more efficient alternative to individual analyses of each outcome. Surprisingly, this is not always the case. In this article we discuss different settings of linear models and compare the multivariate and univariate approaches. We show that for linear regression models, the estimates of the regression parameters associated with covariates that are shared across the outcomes are the same for the multivariate and univariate models while for outcome-specific covariates the multivariate model performs better in terms of efficiency.pt_PT
dc.identifier.citationOliveira, R., & Pinto, A. T. (2015). Analyzing Multiple Outcomes: Is it Really Worth the use of Multivariate Linear Regression? Journal of Biometrics & Biostatistics, 1–6. https://www.hilarispublisher.com/open-access/analyzing-multiple-outcomes-is-it-really-worth-the-use-ofmultivariate-linear-regression-2155-6180-1000256.pdf
dc.identifier.doi10.4172/2155-6180.1000256pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/7601
dc.language.isoengpt_PT
dc.relation.publisherversionhttp://www.omicsonline.org/open-access/analyzing-multiple-outcomes-is-it-really-worth-the-use-ofmultivariate-linear-regression-2155-6180-1000256.php?aid=63373pt_PT
dc.subjectOrdinary least squarespt_PT
dc.subjectCorrelated errorspt_PT
dc.subjectGeneralized least squarespt_PT
dc.subjectMonte Carlopt_PT
dc.titleAnalyzing multiple outcomes: is it really worth the use of multivariate linear regression?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleJournal of Biometrics and Biostatisticspt_PT
oaire.citation.volume6pt_PT
person.familyNameOliveira
person.familyNameTeixeira-Pinto
person.givenNameRosa
person.givenNameArmando
person.identifier.ciencia-idB816-2108-2562
person.identifier.ciencia-id6A1A-BF16-8B2D
person.identifier.orcid0000-0002-3456-0853
person.identifier.orcid0000-0002-9389-2516
person.identifier.ridH-7947-2013
person.identifier.scopus-author-id6602574836
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4fa03d0c-7523-4a29-b485-805c2560c250
relation.isAuthorOfPublicationdd440f5a-8f1b-49cb-832c-afb78adc7234
relation.isAuthorOfPublication.latestForDiscovery4fa03d0c-7523-4a29-b485-805c2560c250

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