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Advisor(s)
Abstract(s)
Hypersensitivity pneumonitis (HP) is an interstitial lung disease that results in parenchymal and small airways inflammation and culminates in breathlessness, negatively impacting patient’s quality of life and survival. HP is initiated by an exaggerated immune response triggered by the inhalation of a variety of environmental antigens. The identification of the triggering antigen is a cornerstone of the diagnostic algorithm, and importantly, exposure avoidance ameliorates the clinical outcomes. However, the inciting antigen is not identified in a large proportion of patients. A difficult to identify, but common inciting antigen, is exposure to household fungi.
Description
Keywords
Hypersensitivity Pneumonitis Interstitial lung disease Household fungi T cell response
Citation
Santos, R. F., Coelho, A. L., Rufo, J. C., Coelho, D., Gonçalves, M., Gonçalves, S. L., Cunha, C., Carvalho, A., Delgado, L., Morais, A., Saraiva, M., & Novais-Bastos, hélder. (2023). Comprehensive assessment of environmental fungus-reactive T cells response in hypersensitivity pneumonitis patients. Livro de Resumos do 16º Encontro de Investigação Jovem da U.Porto, 337–338.